immunology

Engineered natural killer cells track down cancer cells in the bone marrow.

Christopher Klebanoff hopes that his search for a small fraction of cancer-specific antigens will have a big impact on cancer cell therapies.

Low salt intake during pregnancy in mice influences the pruning of extra synapses of the taste circuit later in life.

Timely modulation of a common signaling pathway can preserve influenza memory in lung T cells.

In a race to the tumor, a macrophage’s phenotype can give it a leg up on the competition.

A host lipid-modifying enzyme plays a key role in HIV envelope formation, viral maturation, and infectivity. 

An on-off enzyme switch controls metastasis in mice. 

Clean and dirty mice respond similarly to allergens, challenging the idea that reduced microbial exposure is the primary cause behind the uptick in allergies.

CRISPR-Cas9 editing leads to widespread loss of the targeted chromosome in human T cells, but scientists recently discovered a way to prevent such loss.

Diet influences the microbiome. When new foods enter the mix, it gets complicated.

Researchers developed a “test tube” so tiny that it can hold a single cell. These vials enabled them to connect protein secretion levels with surface markers and transcriptome data from the same cell. 

Simulated microgravity in mice reveals a constellation of genes that may influence muscle weakening during spaceflight.

Dietary changes rapidly alter T cell metabolism, but the effects can be reversed.

CD4 T cells mediate gut symptoms that indicate early Parkinson’s disease.