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How RNAs Called SINEUPs Upregulate Translation
How RNAs Called SINEUPs Upregulate Translation
The recently discovered long noncoding RNAs seem to boost the production of specific proteins in the cell by interacting with RNA-binding proteins, researchers find.
How RNAs Called SINEUPs Upregulate Translation
How RNAs Called SINEUPs Upregulate Translation

The recently discovered long noncoding RNAs seem to boost the production of specific proteins in the cell by interacting with RNA-binding proteins, researchers find.

The recently discovered long noncoding RNAs seem to boost the production of specific proteins in the cell by interacting with RNA-binding proteins, researchers find.

literature, genetics & genomics

Immune Genes Protect Cells from Ebola Virus and SARS-CoV-2
Rachael Moeller Gorman | Dec 1, 2020 | 3 min read
A pathway involved in the adaptive immune system, a relative newcomer in the world of pathogen defense, may have a more ancient role in protecting cells from invading viruses.
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Could AI Make Gene Editing More Accurate?
Ashley Yeager | May 1, 2019 | 3 min read
Machine learning algorithms predict the repairs made to DNA after Cas9 cuts.
literature infographic dna repair
Without This Enzyme, Insertions Thrive in the Yeast Genome
Katarina Zimmer | Mar 1, 2019 | 3 min read
A study underscores the importance of Dna2 in maintaining the integrity of the genetic code.
Alzheimer’s Gene Affects Energy Consumption in Mouse Brains
Sukanya Charuchandra | Oct 1, 2018 | 2 min read
One variant limited the brain’s ability to use glucose.
Genes’ Composition Guides More-Optimal Diets
Ruth Williams | Jun 1, 2017 | 2 min read
Fruit flies and mice grow better and eat less when the amino acid balance of their food reflects that coded by their exomes.
Infographic: Cook Up an Exome-Based Diet
Ruth Williams | May 31, 2017 | 1 min read
See how scientists designed food with amino acid compositions based on protein-coding regions in the genomes of mice and fruit flies.
Noncoding RNA Helps Cells Recover from DNA Damage
Diana Kwon | May 1, 2017 | 2 min read
Scientists discover transcripts from the same gene that can express both proteins and noncoding RNA.
 
Transgenerational Epigenetics Prepares Plants for Drought
Ben Andrew Henry | Jan 1, 2017 | 2 min read
Plants grown in dry soil produce offspring that are hardier in drought conditions, and DNA methylation appears responsible. 
RNA Sequences Don’t Predict In Vivo Transcript Structure
Catherine Offord | Jan 1, 2017 | 3 min read
Eukaryotes prevent secondary RNA structures called G-quadruplexes, commonly observed in vitro, from forming in the cell. 
Infographic: Examining Open Chromatin
Ruth Williams | Dec 31, 2016 | 1 min read
See how researchers visualize regions of active genes.
Infographic: Keeping RNA Structures in Line
Catherine Offord | Dec 31, 2016 | 1 min read
Scientists find fewer RNA G-quadruplexes in vivo than in vitro.
Protozoans Found With No Dedicated Stop Codons
Karen Zusi | Oct 1, 2016 | 3 min read
Some ciliates use the same trio of nucleotides to code for an amino acid and to stop translation.
Some Human Cancers Exhibit Low-grade Inflammation
Alison F. Takemura | Oct 1, 2016 | 2 min read
NSAIDs reduce this "parainflammation," hinting at how they help lower cancer risk.
Ciliates Are Genetic-Code Deviants
Karen Zusi | Sep 30, 2016 | 1 min read
Traditional stop codons have a double meaning in the protozoans' mRNA, sometimes calling for an amino acid during translation.
Scientists Catch Translation in the Act
Ruth Williams | Sep 30, 2016 | 1 min read
Newly developed techniques from four different groups rely on the same basic steps to track translation in live cells.
Aneuploid Responses
Catherine Offord | May 1, 2016 | 2 min read
A recent exchange of papers is divided over the evidence for compensatory gene expression among wild strains of aneuploid yeast.
Managing Methylation
Karen Zusi | Jan 1, 2016 | 2 min read
A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.
Telomerase Overdrive
Ashley P. Taylor | Jan 1, 2016 | 2 min read
Two mutations in a gene involved in telomere extension reverse the gene’s epigenetic silencing.
Metazoans in the DNAi Club
Amanda B. Keener | Jul 1, 2015 | 2 min read
A chance discovery results in the first report of DNA-based gene silencing in an animal.
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