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Mice engineered to overproduce the organelles involved in cell division spontaneously develop malignancies.

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image: Starvation Response Triggers Melanoma Invasion

Starvation Response Triggers Melanoma Invasion

By Catherine Offord | April 1, 2017

Through similar mechanisms, amino acid depletion in culture and cytokine activity in the tumor microenvironment prompt cancer cells to metastasize.

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image: Plant Photoreceptor Doubles as a Thermometer

Plant Photoreceptor Doubles as a Thermometer

By Ben Andrew Henry | February 1, 2017

Warmth acts on a light-sensing protein similarly to the way shade does, setting off a growth spurt in plant seedlings.

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image: Cells Follow Stiffness Gradients by Playing Tug-of-War

Cells Follow Stiffness Gradients by Playing Tug-of-War

By Ben Andrew Henry | December 1, 2016

Cells with the best traction on a substrate pull their neighbors toward firmer ground.

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Results from experiments in mice revise a long-held hypothesis that certain protein scaffolds are needed for synaptic activity.

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image: Some Human Cancers Exhibit Low-grade Inflammation

Some Human Cancers Exhibit Low-grade Inflammation

By Alison F. Takemura | October 1, 2016

NSAIDs reduce this "parainflammation," hinting at how they help lower cancer risk.

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image: Newly Discovered Emergency Responders to Liver Damage

Newly Discovered Emergency Responders to Liver Damage

By Ashley P. Taylor | August 1, 2016

Immune cells called macrophages from the peritoneal cavity of mice migrate to injured livers and aid in repair.

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image: Generating Cardiac Precursor Cells

Generating Cardiac Precursor Cells

By Kerry Grens | June 1, 2016

Researchers derive cardiac precursors to form cardiac muscle, endothelial, and smooth muscle cells in mice.

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image: In Failing Hearts, Cardiomyocytes Alter Metabolism

In Failing Hearts, Cardiomyocytes Alter Metabolism

By Amanda B. Keener | June 1, 2016

While the heart cells normally burn fatty acids, when things go wrong ketones become the preferred fuel source.

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image: Cancer's Vanguard

Cancer's Vanguard

By Catherine Offord | April 1, 2016

Exosomes are emerging as key players in metastasis.

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