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image: Condensin Folds DNA Through Loop Extrusion

Condensin Folds DNA Through Loop Extrusion

By Diana Kwon | June 1, 2018

By observing the activity of a protein complex in real time, researchers have uncovered new evidence for a long-standing theory.

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image: Incomplete Immunity

Incomplete Immunity

By Jim Daley | June 1, 2018

By combining experimental data with computer models, researchers were able to predict a pathogen’s evolution toward more virulence.

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image: Productivity Paradox

Productivity Paradox

By Jim Daley | June 1, 2018

During the last ice age, there wasn’t much plant matter to eat on northern steppes, but herbivorous woolly mammoths were abundant. How did they survive?

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Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.

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In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.

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In response to short DNA fragments, lymphocytes release mitochondrial DNA that helps trigger an immune response.

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A single receptor on natural killer cells recognizes an amino acid sequence conserved across Zika, dengue, and related pathogens.

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image: Microglia Turnover in the Human Brain

Microglia Turnover in the Human Brain

By Shawna Williams | October 1, 2017

Researchers find that about a quarter of the immune cells are replaced every year.

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image: How Immune Receptors Got into Mouse Noses

How Immune Receptors Got into Mouse Noses

By Shawna Williams | September 1, 2017

A study traces proteins’ evolution from the immune to the olfactory system.

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image: Epigenetic Inheritance in Nematodes

Epigenetic Inheritance in Nematodes

By Catherine Offord | July 17, 2017

The memory of a temperature spike can persist for as many as 14 generations in C. elegans.

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