The Literature

» physiology, immunology and genetics & genomics

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image: Telomerase Overdrive

Telomerase Overdrive

By Ashley P. Taylor | January 1, 2016

Two mutations in a gene involved in telomere extension reverse the gene’s epigenetic silencing.

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image: Fanning the Flames

Fanning the Flames

By Kate Yandell | November 1, 2015

Obesity triggers a fatty acid synthesis pathway, which in turn helps drive T cell differentiation and inflammation.

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image: Fat Saps Muscle

Fat Saps Muscle

By Tracy Vence | November 1, 2015

The accumulation of fat within skeletal muscle, as happens with obesity, diminishes muscle performance.

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image: Rethinking Lymphatic Development

Rethinking Lymphatic Development

By Amanda B. Keener | August 1, 2015

Four studies identify alternative origins for cells of the developing lymphatic system, challenging the long-standing view that they all come from veins.

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image: Metazoans in the DNAi Club

Metazoans in the DNAi Club

By Amanda B. Keener | July 1, 2015

A chance discovery results in the first report of DNA-based gene silencing in an animal.

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image: New Immunity

New Immunity

By Kerry Grens | June 1, 2015

A scaffolding protein forms the hub of a newly identified immune pathway in plants.

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image: Not So Noncoding

Not So Noncoding

By Jenny Rood | June 1, 2015

An RNA thought to be noncoding in fact encodes a small protein that regulates calcium uptake in muscle.

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image: Silencing Surprise

Silencing Surprise

By Jenny Rood | June 1, 2015

A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.

3 Comments

image: Looking for Latent HIV

Looking for Latent HIV

By Jenny Rood | May 1, 2015

Sequencing HIV integration sites suggests that clonally expanded T-cell populations may not be the main source of latent virus.

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image: Soluble Signal

Soluble Signal

By Jenny Rood | May 1, 2015

An immune protein previously thought to mark inactive T cells has a free-floating form that correlates with HIV disease progression.

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