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tag physiology cell molecular biology

A Molecular Switch for Bone Loss
Mariella Bodemeier Loayza Careaga, PhD | Jan 23, 2024 | 4 min read
Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Decoding the Cellular Secrets of the Endometrium 
Deanna MacNeil, PhD | Jan 16, 2024 | 3 min read
Endometrial organoids and single cell analyses helped uncover the molecular mechanisms of a rare uterine condition.
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
The image shows two adult prairie voles. The voles have a brown coat and are touching each other’s snouts.
Molecular Signatures of a Broken Heart
Mariella Bodemeier Loayza Careaga, PhD | Sep 8, 2023 | 3 min read
The transcriptional profiles in the brains of prairie voles changed after a long breakup, revealing a molecular shift that might help them cope with the loss of a partner.
The image shows different people exercising in a gym.
What Happens to Muscles During Exercise?
Mariella Bodemeier Loayza Careaga, PhD | Jan 1, 2024 | 2 min read
Exercise changes our muscles, but its molecular effects depend on the type of exercise. 
The figure shows two waves made of DNA double helixes representing gene expression changes in the malaria parasite and its human host. These changes reveal a synchronization between parasite and host.
Malaria Parasites Sync with Hosts’ Molecular Rhythms
Mariella Bodemeier Loayza Careaga, PhD | Sep 1, 2023 | 2 min read
Evidence of malaria parasites aligning with their human hosts may pave the way for new antimalarial agents.
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
The image shows six different panels containing cells. On each panel, the cells are labelled using a different fluorescent dye that highlights features of a specific organelle within the cells.
Cell Painting: Exploring the Richness of Biological Images
Mariella Bodemeier Loayza Careaga, PhD | Sep 8, 2023 | 4 min read
By coloring different organelles simultaneously, cell painting allows scientists to pick up subtle changes in cell function in response to drugs and other perturbations.

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