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physiology

Flat blue line that becomes a pink jagged line and then a flat red line, on a black background.
Emerging from Silence: Capturing the First Heartbeat
Danielle Gerhard, PhD | Sep 27, 2023 | 5 min read
In the developing zebrafish, a noisy and asynchronous activity jumpstarts the heart’s journey to coordinated beating.
Melanocyte stem cells are shown in red and other cell nuclei are shown in blue.
Hair Turns Gray Due to Stuck Stem Cells
Mariella Bodemeier Loayza Careaga, PhD | Sep 8, 2023 | 3 min read
Hair-coloring stem cells must swing back and forth between their maturity states to give hair its color.
Developing Spatial Multiomic Maps
Technique Talk: Developing Spatial Multiomic Maps
The Scientist | 1 min read
Rafael Kramann will discuss spatial transcriptome and epigenome changes to identify injury, repair, and remodeling in myocardial infarction.
An elderly person in beige shirt and a knitted, cream-colored vest holds a wooden walking stick.
New Epigenetic Clocks May Confirm Extreme Age
Ida Emilie Steinmark, PhD | Sep 8, 2023 | 4 min read
How will a new version of epigenetic clocks aimed at validating the age of people older than 100 years of age balance accuracy and anonymity?
The image shows two adult prairie voles. The voles have a brown coat and are touching each other’s snouts.
Molecular Signatures of a Broken Heart
Mariella Bodemeier Loayza Careaga, PhD | Sep 8, 2023 | 3 min read
The transcriptional profiles in the brains of prairie voles changed after a long breakup, revealing a molecular shift that might help them cope with the loss of a partner.
Learn How the Immune System Can Be Trained to Overcome Food Allergies
Retraining the Immune System Cavalry for Food Allergen Peacekeeping Missions
The Scientist | 1 min read
Explore food allergy immunotherapy for reversing patient symptoms.
Image of someone scratching their skin.
A Chronic Itch: Burrowing Beneath the Skin
Brian S. Kim, MD | Sep 8, 2023 | 9 min read
We have barely scratched the surface of itch science and what it indicates about our health.
A fluorescence microscopy image of a common mouse ear with a black background, an embedded bead visible as a white circle, and regenerating tissue around it shown in green.
Mice Heal Themselves in Response to a Common Signaling Molecule
Ida Emilie Steinmark, PhD | Sep 8, 2023 | 4 min read
A newly discovered way to induce scarless healing in mice depends on a highly conserved signaling pathway that is also present in humans.
Peripheral blood mononuclear cells surrounded by red blood cells in circulating blood.
Accelerating Immune Research with Cryopreserved Peripheral Blood Mononuclear Cells
The Scientist and MilliporeSigma | 3 min read
Commerically-available peripheral blood mononuclear cells offer a well-characterized, accessible, and consistent model for immunology and therapeutic development.
The figure shows two waves made of DNA double helixes representing gene expression changes in the malaria parasite and its human host. These changes reveal a synchronization between parasite and host.
Malaria Parasites Sync with Hosts’ Molecular Rhythms
Mariella Bodemeier Loayza Careaga, PhD | Sep 1, 2023 | 2 min read
Evidence of malaria parasites aligning with their human hosts may pave the way for new antimalarial agents.
The image shows round-shaped glial cells in red and elongated neuronal cells in green surrounding the glial cells.
How Stress Inflames the Gut
Mariella Bodemeier Loayza Careaga, PhD | Sep 1, 2023 | 2 min read
In mice, chronically high levels of stress hormones worsen bowel inflammation.
A Scientific Figure of Speech
Science Philosophy in a Flash - A Scientific Figure of Speech
Iris Kulbatski, PhD | 1 min read
Beate Peter shares how her “scientific bilingualism” is the driving force behind her philosophy of science.
The image illustrates the relationship between the brain and gut in humans.
A Novel Tool to Explore the Gut-brain Connection
Anna Napolitano, PhD | Aug 28, 2023 | 3 min read
Scientists used a vibrating capsule to assess people’s gut sensitivities and understand how the brain interprets these signals.  
Image representing states of consciousness
High Time: The Roles of Endogenous Psychedelics
Iris Kulbatski, PhD | Aug 1, 2023 | 2 min read
Steven Barker is on a forty-seven-year-long journey to understand the mind-blowing science of psychedelics.
Exosomes, microvesicles, and apoptotic bodies: The three major types of extracellular vesicle.
Extracellular Vesicles: Applications and Potential
Beckman Coulter Life Sciences | 1 min read
Explore why extracellular vesicles are attractive candidates for new therapeutic approaches.
The image shows a brain section of the mouse amygdala. Using fluorescent markers, the expression of synapses is shown in purple, while neurons are shown as red dots and the microRNA miR-483-5p is shown as green dots.
A Brain MicroRNA Curbs Anxiety
Mariella Bodemeier Loayza Careaga, PhD | Aug 1, 2023 | 2 min read
Upregulation of a specific microRNA in the brain lessened anxiety and reduced the expression of stress-related genes in mice. 
Close-up of women’s hands using lancet on finger.
A Noninvasive Glucose Monitor for Managing Diabetes
Natalia Mesa, PhD | Jul 20, 2023 | 3 min read
A new, invisible fluorescent patch continuously monitors blood glucose levels in mice.
Developing Aptamer Biosensor Technology for Diagnostics and Therapeutics
Expanding the Available Target Range for New Drugs and Diagnostics with Aptamers
The Scientist and aptamer Group | 1 min read
In this roundtable discussion, an expert panel will discuss how the latest applications of aptamer technology are enabling innovation across the life sciences by replacing antibodies.
Old brown dog with gray on its face and neck
Aging Dogs Provide Insights for Human Longevity
Hannah Thomasy, PhD, Drug Discovery News | Jul 19, 2023 | 6 min read
Biogerontologist Matt Kaeberlein studies aging pets to determine how to improve healthspan in dogs and their humans.
Patient with skin blisters being swabbed by gloved hand
Delivering Gene Therapies in Utero 
Natalia Mesa, PhD | Jul 18, 2023 | 3 min read
By delivering mRNA to the skin of mice in utero, researchers showed a proof-of-concept for shuttling gene therapies to skin cells before birth.
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