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tag structural biology immunology cell molecular biology microbiology

Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Molecular Biology
The Scientist Staff | Jul 24, 1994 | 2 min read
D.H. Fremont, M. Matsumura, E.A. Stura, P.A. Peterson, I.A. Wilson, "Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb," Science, 257:919-27, 1992. Ian A. Wilson (Department of Molecular Biology, Scripps Research Institute, La Jolla, Calif.): "One of the major issues in molecular immunology is determining how a limited number of major histocompatibility complex (MHC) molecules in any individual can
Molecular Biology
The Scientist Staff | Jul 24, 1994 | 2 min read
D.H. Fremont, M. Matsumura, E.A. Stura, P.A. Peterson, I.A. Wilson, "Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb," Science, 257:919-27, 1992. Ian A. Wilson (Department of Molecular Biology, Scripps Research Institute, La Jolla, Calif.): "One of the major issues in molecular immunology is determining how a limited number of major histocompatibility complex (MHC) molecules in any individual can
Collage of images including sperm, bacteria, coral, and an illustration of a researcher
Our Favorite Cell and Molecular Biology Stories of 2021
Jef Akst | Dec 2, 2021 | 3 min read
Beyond The Scientist’s coverage of COVID-19’s molecular underpinnings were many other stories highlighting the advances made in scientists’ understanding of the biology of cells.
Structural Biology
The Scientist Staff | Mar 2, 1997 | 2 min read
Edited by: Karen Young Kreeger J.P. Griffith, J.L. Kim, E.E. Kim, M.D. Sintchak, J.A. Thomson, M.J. Fitzgibbon, M.A. Fleming, P.R. Caron, K. Hsiao, M.A. Navia, "X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex," Cell, 82:507-22, 1995. (Cited in close to 70 publications as of February 1997) Comments by James P. Griffith and Joseph L. Kim, Vertex Pharmaceuticals Inc., Cambridge, Mass. FK506 is an immunosuppressant drug used for preventing graft
Molecular Biology
The Scientist Staff | Sep 1, 1991 | 1 min read
S. Ghosh, D. Baltimore, "Activation in vitro of NF-kB by phosphorylation of its inhibitor IkB," Nature, 344:678-82, 1990. Sankar Ghosh (Whitehead Institute for Biomedical Research, Cambridge, Mass.): "This paper brings together two areas of rapidly moving research: the role of protein phosphorylation and control of transcriptional regulation. The inhibitor IkB not only keeps the transcription factor NF-kB in the cytoplasm--away from DNA--but also directly prevents it from binding to DNA. By sh
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
Individual bacterial transcriptomes each plotted as a single point create a ring-shaped structure.
Rapidly Dividing Bacteria Coordinate Gene Expression and Replication
Kamal Nahas, PhD | Mar 15, 2024 | 4 min read
E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible.
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | Feb 13, 2024 | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.

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