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tag structural biology immunology cell molecular biology developmental biology

Developmental Biology
The Scientist Staff | Jan 3, 1999 | 3 min read
L.B. Zimmerman, J.M. De Jesús-Escobar, R.M. Harland, "The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4," Cell, 86:599-606, 1996. (Cited in more than 180 papers since publication) Comments by Richard M. Harland, Choh Hao Li professor of biochemistry and molecular biology, University of California, Berkeley Richard M. Harland Researchers had long suspected that the protein noggin's interaction with bone morphogenetic proteins (BMPs) dictated devel
Developmental Biology
The Scientist Staff | Apr 1, 1996 | 3 min read
Edited by Karen Young Kreeger H. Roelink, A. Augsburger, J. Heemskerk, V. Korzh, S. Norlin, A. Ruiz i Altaba, Y. Tanabe, M. Placzek, T. Edlund, T.M. Jessell, J. Dodd, "Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord," Cell, 76:761-75, 1994. (Cited in nearly 90 publications as of February 1996) Comments by Henk Roelink, University of Washington SIGNALS FROM SONIC HEDGEHOG: Using cDNA, University of Washington's Henk Roelink and col
Molecular Biology
The Scientist Staff | Feb 17, 1991 | 3 min read
R.J. Bandziulis, M.S. Swanson, G. Dreyfuss, "RNA-binding proteins as developmental regulators," Genes and Development, 3, 431-7, April 1989. Gideon Dreyfuss (University of Pennsylvania School of Medicine, Philadelphia): "Protein structural comparisons led to the discovery of identifying and unifying features shared by RNA-binding proteins of the nucleus and cytoplasm. Many of these ribonucleoproteins contain an RNA-binding domain (RBD) of approximately 90 amino acids. This amino acid sequence
Molecular Biology
The Scientist Staff | Jul 24, 1994 | 2 min read
D.H. Fremont, M. Matsumura, E.A. Stura, P.A. Peterson, I.A. Wilson, "Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb," Science, 257:919-27, 1992. Ian A. Wilson (Department of Molecular Biology, Scripps Research Institute, La Jolla, Calif.): "One of the major issues in molecular immunology is determining how a limited number of major histocompatibility complex (MHC) molecules in any individual can
Molecular Biology
The Scientist Staff | Jul 24, 1994 | 2 min read
D.H. Fremont, M. Matsumura, E.A. Stura, P.A. Peterson, I.A. Wilson, "Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb," Science, 257:919-27, 1992. Ian A. Wilson (Department of Molecular Biology, Scripps Research Institute, La Jolla, Calif.): "One of the major issues in molecular immunology is determining how a limited number of major histocompatibility complex (MHC) molecules in any individual can
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Structural Biology
The Scientist Staff | Mar 2, 1997 | 2 min read
Edited by: Karen Young Kreeger J.P. Griffith, J.L. Kim, E.E. Kim, M.D. Sintchak, J.A. Thomson, M.J. Fitzgibbon, M.A. Fleming, P.R. Caron, K. Hsiao, M.A. Navia, "X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex," Cell, 82:507-22, 1995. (Cited in close to 70 publications as of February 1997) Comments by James P. Griffith and Joseph L. Kim, Vertex Pharmaceuticals Inc., Cambridge, Mass. FK506 is an immunosuppressant drug used for preventing graft
Molecular Biology
The Scientist Staff | Feb 3, 1991 | 3 min read
T. Hai, F. Liu, W.J. Coukos, M.R. Green, "Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers," Genes and Development, 3, 2083-90, December 1989. Michael R. Green (University of Massachusetts Medical Center, Worcester, Mass.): "I suspect that this paper may have attracted more than the usual attention because it is relevant to several research areas, and some of the results were unexpected. We and others had bee
Molecular Biology
The Scientist Staff | Sep 1, 1991 | 1 min read
S. Ghosh, D. Baltimore, "Activation in vitro of NF-kB by phosphorylation of its inhibitor IkB," Nature, 344:678-82, 1990. Sankar Ghosh (Whitehead Institute for Biomedical Research, Cambridge, Mass.): "This paper brings together two areas of rapidly moving research: the role of protein phosphorylation and control of transcriptional regulation. The inhibitor IkB not only keeps the transcription factor NF-kB in the cytoplasm--away from DNA--but also directly prevents it from binding to DNA. By sh
Top 7 in developmental biology
Bob Grant | Dec 17, 2010 | 3 min read
A snapshot of the most highly ranked articles in developmental biology, from Faculty of 1000

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