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Lab-Grown Mouse Embryos Form Limbs and Organs
Lab-Grown Mouse Embryos Form Limbs and Organs
The embryos completed one-third of their total gestation outside of a uterus.
Lab-Grown Mouse Embryos Form Limbs and Organs
Lab-Grown Mouse Embryos Form Limbs and Organs

The embryos completed one-third of their total gestation outside of a uterus.

The embryos completed one-third of their total gestation outside of a uterus.

developmental biology, genetics & genomics

A Simple Genetic Change Adds Limb-Like Bones to Zebrafish Fins
Abby Olena, PhD | Feb 5, 2021 | 4 min read
A gain-of-function mutation in a single gene reveals ancient limb-forming capacity that has been preserved for hundreds of millions of years.
Siobhán Brady Uses Big Data to Investigate Plant Development
Shawna Williams | Feb 1, 2021 | 3 min read
The University of California, Davis, professor is a pioneer in teasing apart the changes in gene expression that drive root development.
Identical Twins Accumulate Genetic Differences in the Womb
Catherine Offord | Jan 7, 2021 | 4 min read
DNA replication errors during cell division cause monozygotic twins to diverge from each other even during the earliest stages of development, a new study finds.
Kathryn Anderson, forward genetics, genetics & genomics, model organisms, Toll, hedgehog, embryogenesis, developmental biology, cell differentiation, cilia,
Developmental Biologist Kathryn Anderson Dies at 68
Amanda Heidt | Jan 6, 2021 | 4 min read
The Sloan Kettering researcher used mutagenic screening to probe genes and molecular pathways, including Toll and Hedgehog, essential to development in fruit flies and mice.
model organism, zebrafish, sponge, cell &molecular biology, genetics & genomics, enhancer, transcription, non-coding DNA, gene regulation, evolution
Regulators of Gene Activity in Animals Are Deeply Conserved
Amanda Heidt | Nov 6, 2020 | 5 min read
Enhancers, short regions of DNA that direct gene expression, of species separated by 700 million years of evolution worked interchangeably, according to a new study.
Infographic: Anatomical Construction by Cell Collectives
Michael Levin | Sep 1, 2020 | 3 min read
Understanding this complex and still largely enigmatic process will pave the way for researchers to control the development of new morphologies.
How Groups of Cells Cooperate to Build Organs and Organisms
Michael Levin | Sep 1, 2020 | 10+ min read
Understanding biology’s software—the rules that enable great plasticity in how cell collectives generate reliable anatomies—is key to advancing tissue engineering and regenerative medicine.
Gene Splicing Pioneer Dale Kaiser Dies
Ashley Yeager | Jun 29, 2020 | 5 min read
Working with a virus that infects bacteria, the Stanford University biochemist and developmental biologist helped to develop a way to stitch DNA together, a discovery that gave rise to genetic engineering.
How a Pea Aphid Decides to Make Wings or Not
Viviane Callier | Jun 1, 2020 | 2 min read
Wing development in females is environmentally controlled, but in males, an insertion on the sex chromosome appears to dictate whether the insects grow wings, according to a study.
Swamp Wallabies Can Have Two Separate Pregnancies at Once
Lisa Winter | Mar 3, 2020 | 3 min read
Before the joey is born, another pregnancy has already started.
Killifish Embryos Pause Development Without Consequence: Study
Lisa Winter | Feb 21, 2020 | 3 min read
Contrary to popular thinking, the period of arrested development is an active state of maintaining muscle integrity.
Transposons Identified as Likely Cause of Undiagnosed Diseases
Jef Akst | Jan 13, 2020 | 4 min read
A tool for identifying jumping gene insertions in DNA sequencing data turns up possible explanations for four patients’ rare developmental disorders.
Deafness Gene GJB2 Edited in Human Eggs
Emily Makowski | Oct 18, 2019 | 2 min read
The research, led by Russian biologist Denis Rebrikov, has not led to the birth of gene-edited babies—yet.
albino lizard hatchling
Image of the Day: Gene-Edited Reptiles
Nicoletta Lanese | Sep 4, 2019 | 2 min read
Scientists injected unfertilized anole lizard eggs with CRISPR-Cas9 to produce albino offspring.
Genes that Are Harmless on Their Own Cause Disease When Combined
Chia-Yi Hou | Sep 1, 2019 | 3 min read
A case study of a family demonstrates that different genetic mutations from the two parents cause severe heart disease symptoms in the children.
Japanese grass pufferfish (Takifugu niphobles) CT scan
Pufferfish Spines Shaped by Same Genes as Feathers and Fish Scales
Nicoletta Lanese | Jul 29, 2019 | 3 min read
To see if the spiky fish shares signaling pathways found in other organisms, scientists scooped up specimens during a mating frenzy on the shores of Japan.
crispr baby he jiankui gene editing genome fertility clinic emails
Fertility Clinics Sought Advice from Scientist Who CRISPRed Babies
Chia-Yi Hou | May 29, 2019 | 1 min read
Emails reveal that a facility in Dubai and others have asked geneticist He Jiankui for help in gene-editing embryos.
atlantic killifish Fundulus heteroclitus
Killifish Survive Polluted Waters Thanks to Genes from Another Fish
Emma Yasinski | May 6, 2019 | 4 min read
Gulf killifish have made a stunning comeback in Houston with the help of genetic mutations imported from interspecies mating with Atlantic killifish.
rhesus macaque monkey gene editing genetic modification
Monkeys Genetically Edited to Mimic Human Brain Development
Chia-Yi Hou | Apr 10, 2019 | 2 min read
Rhesus monkeys engineered to express a human gene reportedly show delayed brain development and better short-term memory. Fellow scientists are raising ethical red flags.
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