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image: Condensin Folds DNA Through Loop Extrusion

Condensin Folds DNA Through Loop Extrusion

By Diana Kwon | June 1, 2018

By observing the activity of a protein complex in real time, researchers have uncovered new evidence for a long-standing theory.

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Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.

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In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.

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In response to short DNA fragments, lymphocytes release mitochondrial DNA that helps trigger an immune response.

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A single receptor on natural killer cells recognizes an amino acid sequence conserved across Zika, dengue, and related pathogens.

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image: Microglia Turnover in the Human Brain

Microglia Turnover in the Human Brain

By Shawna Williams | October 1, 2017

Researchers find that about a quarter of the immune cells are replaced every year.

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Pauses may help cells fine-tune gene expression.

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image: How Immune Receptors Got into Mouse Noses

How Immune Receptors Got into Mouse Noses

By Shawna Williams | September 1, 2017

A study traces proteins’ evolution from the immune to the olfactory system.

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image: Researchers Identify Clue to Asymmetric Cell Division

Researchers Identify Clue to Asymmetric Cell Division

By Shawna Williams | September 1, 2017

Phosphorylation of a surface protein on endosomes is key to the organelles’ uneven distribution in daughter cells.

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image: Epigenetic Inheritance in Nematodes

Epigenetic Inheritance in Nematodes

By Catherine Offord | July 17, 2017

The memory of a temperature spike can persist for as many as 14 generations in C. elegans.

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