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image: Managing Methylation

Managing Methylation

By Karen Zusi | January 1, 2016

A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.

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image: Telomerase Overdrive

Telomerase Overdrive

By Ashley P. Taylor | January 1, 2016

Two mutations in a gene involved in telomere extension reverse the gene’s epigenetic silencing.

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image: Metazoans in the DNAi Club

Metazoans in the DNAi Club

By Amanda B. Keener | July 1, 2015

A chance discovery results in the first report of DNA-based gene silencing in an animal.

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image: Not So Noncoding

Not So Noncoding

By Jenny Rood | June 1, 2015

An RNA thought to be noncoding in fact encodes a small protein that regulates calcium uptake in muscle.

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image: Silencing Surprise

Silencing Surprise

By Jenny Rood | June 1, 2015

A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.

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image: Looking for Latent HIV

Looking for Latent HIV

By Jenny Rood | May 1, 2015

Sequencing HIV integration sites suggests that clonally expanded T-cell populations may not be the main source of latent virus.

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image: Rethinking Telomeres

Rethinking Telomeres

By Kate Yandell | March 1, 2015

Not only do telomeres protect the ends of chromosomes, they also modulate gene expression over cells’ lifetimes.

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image: Nibbled? No Problem

Nibbled? No Problem

By Ashley P. Taylor | February 1, 2015

Making extra copies of their genomes allows some plants to better withstand damage.

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image: A Long Line of LINEs

A Long Line of LINEs

By Kate Yandell | September 1, 2014

Different mechanisms repress mobile DNA elements in human embryonic stem cells depending on the elements’ evolutionary ages.

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image: Sexless Hook-Up

Sexless Hook-Up

By Jyoti Madhusoodanan | September 1, 2014

Genome fusion at stem graft junctions can generate new plant species.

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