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image: Inner Ear Undertakers

Inner Ear Undertakers

By | September 1, 2015

Support cells in the inner ear respond differently to two drugs that kill hair cells.

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image: The Regenerators

The Regenerators

By | September 1, 2015

A molecular signature makes it possible to trace the details of hair cell replacement in the mammalian inner ear.

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image: Sponging Up Phosphorus

Sponging Up Phosphorus

By | July 1, 2015

Symbiotic bacteria in Caribbean reef sponges store polyphosphate granules, possibly explaining why phosphorous is so scarce in coral reef ecosystems.

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image: The Origins of O

The Origins of O

By | May 1, 2015

A strain of HIV that has afflicted more than 100,000 people emerged from gorillas.

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image: Manipulative Microbiomes

Manipulative Microbiomes

By | April 1, 2015

Gut bacteria control tumor growth via the mammalian immune system.

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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Growth Hormone Guidance

Growth Hormone Guidance

By | March 1, 2015

Intact growth hormone signaling pathways are needed for methionine restriction to extend mouse lifespan.

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image: Long Live Collagen

Long Live Collagen

By | March 1, 2015

Increased collagen expression is a common feature of many different pathways to extended longevity in worms.

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image: Polymerase Pieces

Polymerase Pieces

By | December 1, 2014

Researchers discover a new subunit of a bacterial RNA polymerase—as well as hints of its potential role in defending against viruses.

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