Critic at Large

» ecology, disease/medicine and policy

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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image: Body, Heal Thyself

Body, Heal Thyself

By | September 1, 2015

Reviving a decades-old hypothesis of autoimmunity

8 Comments

image: Hurdles for Hearing Restoration

Hurdles for Hearing Restoration

By | September 1, 2015

Given the diverse cell types and complex structure of the human inner ear, will researchers ever be able to re-create it?

1 Comment

image: Control ALT, Delete Cancer

Control ALT, Delete Cancer

By , , and | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

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image: The Challenges of Precision

The Challenges of Precision

By | April 1, 2015

Researchers face roadblocks to treating an individual patient’s cancer as a unique disease.

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image: Facing Down Emerging Viruses

Facing Down Emerging Viruses

By | February 1, 2015

A better knowledge of the pathogenesis of emerging zoonotic diseases is crucial if we want to prepare for “the next Ebola.”

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image: Overspending on Overhead

Overspending on Overhead

By | February 1, 2015

Federal research dollars are needlessly wasted as scientists spend more and more of their time trying to recoup operational costs.

5 Comments

image: A Matter of Size

A Matter of Size

By | August 1, 2014

Erroneous characterization of nanomaterials can misinform the study of a new medicine’s safety and efficacy.

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image: Wild Relatives

Wild Relatives

By , , and | June 1, 2014

As rich sources of genetic diversity, the progenitors and kin of today’s food crops hold great promise for improving production in agriculture’s challenging future.

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image: Psychiatry: An SOS Call

Psychiatry: An SOS Call

By | May 1, 2014

Social policies shaped the practice of psychiatry in the past. As the discipline becomes ever more scientific, the effects of social policy on patient well-being must not be ignored.

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