Critic at Large

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image: Opinion: Understanding and Coping With Rising Publication Costs

Opinion: Understanding and Coping With Rising Publication Costs

By M. Bishr Omary and Theodore S. Lawrence | September 1, 2017

As article processing charges top $5,000 at some research journals, authors and institutions have means of negotiating better deals or finding less expensive options.

0 Comments

image: Opinion: Why I Published in a Predatory Journal

Opinion: Why I Published in a Predatory Journal

By John H. McCool | April 6, 2017

Our totally bogus case report swiftly passed muster, with only minor revisions requested.

12 Comments

Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

0 Comments

image: Opinion: Improving FDA Evaluations Without Jeopardizing Safety and Efficacy

Opinion: Improving FDA Evaluations Without Jeopardizing Safety and Efficacy

By John D. Loike and Jennifer Miller | February 1, 2017

What can be done to lower development costs and drug prices?

4 Comments

image: Opinion: Ethical Considerations of “Three-Parent” Babies

Opinion: Ethical Considerations of “Three-Parent” Babies

By John D. Loike and Nancy Reame | December 22, 2016

Mitochondrial replacement therapy raises important societal and ethical concerns, but should be embraced for its utility in preventing disease.

0 Comments

image: The Age of Pharmabrewing

The Age of Pharmabrewing

By Laura Marengo and John D. Loike | January 1, 2016

We should not resist developing opiate-producing GM yeast for fear of the technology falling into the wrong hands.

0 Comments

image: Body, Heal Thyself

Body, Heal Thyself

By Jason Liebowitz | September 1, 2015

Reviving a decades-old hypothesis of autoimmunity

8 Comments

image: Hurdles for Hearing Restoration

Hurdles for Hearing Restoration

By Bernd Fritzsch | September 1, 2015

Given the diverse cell types and complex structure of the human inner ear, will researchers ever be able to re-create it?

1 Comment

image: When Does a Smart Mouse Become Human?

When Does a Smart Mouse Become Human?

By John D. Loike | July 1, 2015

Ethical issues attend the creation of animal-human chimeras.

1 Comment

image: Control ALT, Delete Cancer

Control ALT, Delete Cancer

By Haroldo Silva, David Halvorsen, and Jeremy D. Henson | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

1 Comment

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