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Critic at Large

» disease/medicine, policy, public health and cancer

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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image: Pet Scans

Pet Scans

By Timothy M. Fan, Amy K. LeBlanc, and Nicola Mason | April 1, 2016

Studying tumor development and treatment in dogs and cats, in parallel with research on rodents and humans, could improve the successful translation of new cancer drugs.

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image: Body, Heal Thyself

Body, Heal Thyself

By Jason Liebowitz | September 1, 2015

Reviving a decades-old hypothesis of autoimmunity

8 Comments

image: Hurdles for Hearing Restoration

Hurdles for Hearing Restoration

By Bernd Fritzsch | September 1, 2015

Given the diverse cell types and complex structure of the human inner ear, will researchers ever be able to re-create it?

1 Comment

image: Control ALT, Delete Cancer

Control ALT, Delete Cancer

By Haroldo Silva, David Halvorsen, and Jeremy D. Henson | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

1 Comment

image: The Challenges of Precision

The Challenges of Precision

By Adam Marcus | April 1, 2015

Researchers face roadblocks to treating an individual patient’s cancer as a unique disease.

1 Comment

image: Facing Down Emerging Viruses

Facing Down Emerging Viruses

By Michal Barski | February 1, 2015

A better knowledge of the pathogenesis of emerging zoonotic diseases is crucial if we want to prepare for “the next Ebola.”

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image: Overspending on Overhead

Overspending on Overhead

By Viviane Callier | February 1, 2015

Federal research dollars are needlessly wasted as scientists spend more and more of their time trying to recoup operational costs.

5 Comments

image: A Matter of Size

A Matter of Size

By Scott McNeil | August 1, 2014

Erroneous characterization of nanomaterials can misinform the study of a new medicine’s safety and efficacy.

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image: Psychiatry: An SOS Call

Psychiatry: An SOS Call

By Robert E. Becker | May 1, 2014

Social policies shaped the practice of psychiatry in the past. As the discipline becomes ever more scientific, the effects of social policy on patient well-being must not be ignored.

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