ADVERTISEMENT
A photo of a dish in which cells, which look like small dots, have been enlarged and stained to make them visible to the naked eye.
New Swelling Technique Makes Cells Visible to the Naked Eye
A new technique, called Unclearing Microscopy, physically inflates and then stains cells to circumvent the need for expensive microscopes.
New Swelling Technique Makes Cells Visible to the Naked Eye
New Swelling Technique Makes Cells Visible to the Naked Eye

A new technique, called Unclearing Microscopy, physically inflates and then stains cells to circumvent the need for expensive microscopes.

A new technique, called Unclearing Microscopy, physically inflates and then stains cells to circumvent the need for expensive microscopes.

techniques, microscopy

2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Conceptual image of blue neurons with glowing segments over blue background.
CRACK Method Reveals Novel Neuron Type in Mouse Brain
Dan Robitzski | Apr 18, 2022 | 3 min read
A new technique reveals cells’ precise locations and functions in the brain. Its developers have already used it to identify a previously unknown neuron type.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
A scanning electron micrograph of a coculture of E. coli and Acinetobacter baylyi. Nanotubes can be seen extending from the E. coli.
What’s the Deal with Bacterial Nanotubes?
Sruthi S. Balakrishnan | Jun 1, 2021 | 10+ min read
Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?
An illustration of a flask of bacteria, a weighted microscope slide, and two bacteria exchanging materials via nanotubes.
Infographic: Sources of Variation in Bacterial Nanotube Studies
Sruthi S. Balakrishnan | Jun 1, 2021 | 2 min read
Differences in how researchers prepare and image samples can lead to discrepancies in their results.
Ibrahim Cissé’s Tools Provide a Lens to Watch RNA Production
Jef Akst | Sep 1, 2020 | 3 min read
The MIT physicist has demonstrated the importance of clusters of RNA polymerase and other transcription mediators in regulating RNA production.
Microscopy and Imaging Leader Shinya Inoué Dies
Jef Akst | Oct 7, 2019 | 1 min read
The long-time Marine Biological Laboratory scientist was known for using his own hand-built microscopes to image the dynamics of live cells.
traced mouse neurons
Image of the Day: Brain Map
Nicoletta Lanese | Sep 6, 2019 | 1 min read
Scientists traced 1,000 neurons through the mouse brain, uncovering new details about how the organ is wired.
Richard Van Duyne
Chemist Richard Van Duyne Dies
Catherine Offord | Aug 16, 2019 | 3 min read
The Northwestern University professor developed surface-enhanced Raman spectroscopy, an invaluable technique for detecting and identifying individual molecules.
SLAP microscope
Image of the Day: Super Speedy Microscopy
Nicoletta Lanese | Aug 9, 2019 | 1 min read
Two-photon imaging captures chemical signaling between live mouse neurons on a millisecond timescale.
dna microscopy visualization RNA cDNA mRNA transcripts cell biology
New Technique Maps RNAs in Cells Without a Microscope
Kerry Grens | Jun 20, 2019 | 1 min read
DNA microscopy pinpoints the locations of transcripts by laying a grid of tags over the molecules and labeling each connection.
Pseudomonas aeruginosa
How Bacteria “Walk” Across a Surface
Diana Kwon | Jun 1, 2019 | 3 min read
Scientists identify the coordinated sequence of pili movements that Pseudomonas aeruginosa use to move.
MO infographic june the scientist
Infographic: High Precision Magnetic Tweezers
Ruth Williams | Jun 1, 2019 | 1 min read
Microscope-mounted magnets with computerized feedback control allow precision manipulations of intracellular objects.
magnetic tweezers
Intracellular Magnetic Manipulations
Ruth Williams | Jun 1, 2019 | 2 min read
Optimized tweezers enable precise 3-D manipulations of a cell’s organelles.
structures in a human cell
Deep Learning Algorithms Identify Structures in Living Cells
Diana Kwon | May 1, 2019 | 4 min read
Researchers are using artificial intelligence to pick out the features of brightfield microscopy images.
New Technique Captures Entire Fly Brain in 3D
Carolyn Wilke | Jan 18, 2019 | 2 min read
The method combines two approaches to reveal a high-resolution map of all 40 million synapses.
AI Networks Generate Super-Resolution from Basic Microscopy
Jef Akst | Dec 17, 2018 | 3 min read
A new study uses deep learning to improve the resolution of biological images, but elicits skepticism about its ability to enhance snapshots of sample types that it has never seen before.
Image of the Day: Bad Behavior
Kerry Grens | Dec 12, 2018 | 1 min read
A deep learning program can identify cells with higher metastatic potential based on the way they look and move.
Sounding Out Cell Stickiness
Ruth Williams | Dec 1, 2018 | 3 min read
Acoustic forces can be used to differentiate adherent from non-adherent cells.
ADVERTISEMENT