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image: Of Mice and Metastasis

Of Mice and Metastasis

By Amanda B. Keener | April 1, 2018

Tools for studying how cancer spreads

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image: New Methods to Detect CRISPR Off-Target Mutations

New Methods to Detect CRISPR Off-Target Mutations

By Sandeep Ravindran | March 1, 2018

Researchers have developed a variety of techniques to detect when CRISPR misses the mark.

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image: High-Throughput Epigenetics Analyses

High-Throughput Epigenetics Analyses

By Jyoti Madhusoodanan | January 1, 2018

Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.

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image: Pinpointing the Culprit

Pinpointing the Culprit

By Rachel Berkowitz | June 1, 2017

Identifying immune cell subsets with CyTOF

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image: A Selection of CRISPR Proof-of-Principle Studies

A Selection of CRISPR Proof-of-Principle Studies

By Kelly Rae Chi | March 1, 2017

Advice on how to deploy the latest techniques in your own lab

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image: Discovering Novel Antibiotics

Discovering Novel Antibiotics

By Sandeep Ravindran | February 1, 2017

Three methods identify and activate silent bacterial gene clusters to uncover new drugs

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image: Characterizing the Imprintome

Characterizing the Imprintome

By Amber Dance | January 1, 2017

Three techniques for identifying the collection of maternal and paternal genes silenced in offspring

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image: Using Raman Spectroscopy to Identify Cell Types

Using Raman Spectroscopy to Identify Cell Types

By Jyoti Madhusoodanan | December 1, 2016

Improvements in instruments and statistical tools allow the capture and analysis of large data sets.

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image: Techniques for Assessing Genomic Copy Number Variations

Techniques for Assessing Genomic Copy Number Variations

By Sarah C.P. Williams | October 1, 2016

As the importance of genomic copy number variations for health and disease becomes clearer, researchers are creating new ways to detect these changes in the genome.

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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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