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tag cancer genetics genomics bioinformatics mass spectrometry

One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Epigenetic Changes Drive Cancer 
Rebecca Roberts, PhD | Nov 28, 2023 | 3 min read
An analysis of almost 700 different tumors revealed that DNA methylation drives tumorigenesis just like genetic mutations do. 
multicolor DNA sequencing gel
Genetic Mutations Can Be Benign or Cancerous—a New Method to Differentiate Between Them Could Lead to Better Treatments
Ryan Layer, The Conversation | May 27, 2022 | 5 min read
Tumors contain thousands of genetic changes, but only a few are actually cancer-causing. A quicker way to identify these driver mutations could lead to more targeted cancer treatments.
Understanding Cancer Evolution Through the Lens of Single Cell Genomics
Understanding Cancer Evolution Through the Lens of Single Cell Genomics
The Scientist | Oct 14, 2021 | 1 min read
Nicholas Navin and Lars Velten discuss sampling, sequencing, and tracing single cells to study how cancer cells adapt to various environments.
An automated sampler that is collecting a sample from a sewer line.
Tracking Community Health Through Wastewater Surveillance
Charlene Lancaster, PhD | Feb 1, 2024 | 8 min read
By monitoring disease biomarkers within wastewater, researchers gain insight into disease prevalence within communities.
Histological slide showing cancerous prostate tissue
2D Genetic Map of Prostate Cells Charts Cancer Growth
Holly Barker, PhD | Aug 23, 2022 | 4 min read
An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors.
Mass Spectrometry and Proteomics
Angelo DePalma | Aug 24, 2003 | 9 min read
Courtesy of Thermo Electron For years, mass spectrometry has been de rigeur in chemistry labs. Recently, though, it has become a mainstay of proteomics research, too. Two years ago, investment bank UBS Warburg identified proteomics as the fastest- growing application of mass spectrometry, a prediction borne out at this year's American Society for Mass Spectrometry (ASMS) annual meeting, where more than 1,100 of 2,227 presentations discussed some aspect of proteomics. It took a confluence of t
electron micrograph of grey cancer cell, with two red T cells stuck to the side
Translation of “Jumping Genes” Creates Cancer Therapy Targets
Natalia Mesa, PhD | Mar 29, 2023 | 4 min read
Researchers find many tumor-specific antigens form when cancer genes and transposable elements link up.
Bioinformatics, Genomics, and Proteomics
Christopher Smith | Nov 26, 2000 | 10+ min read
Data Mining Software for Genomics, Proteomics and Expression Data (Part 1) Data Mining Software for Genomics, Proteomics and Expression Data (Part 2) High-throughput (HT) sequencing, microarray screening and protein expression profiling technologies drive discovery efforts in today's genomics and proteomics laboratories. These tools allow researchers to generate massive amounts of data, at a rate orders of magnitude greater than scientists ever anticipated. Initiatives to sequence entire genom
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.

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