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image: Drugging the Disorderome

Drugging the Disorderome

By Amber Dance | October 1, 2017

Strategies for targeting intrinsically disordered proteins

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image: Ready, Set, Grow

Ready, Set, Grow

By Amber Dance | September 1, 2017

How to culture stem cells without depending on mouse feeder cells

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image: Pinpointing the Culprit

Pinpointing the Culprit

By Rachel Berkowitz | June 1, 2017

Identifying immune cell subsets with CyTOF

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image: How to Track Cell Lineages As They Develop

How to Track Cell Lineages As They Develop

By Kelly Rae Chi | December 1, 2016

Sequencing and gene-editing advances make tracing a cells journey throughout development easier than ever.

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image: Techniques for Assessing Genomic Copy Number Variations

Techniques for Assessing Genomic Copy Number Variations

By Sarah C.P. Williams | October 1, 2016

As the importance of genomic copy number variations for health and disease becomes clearer, researchers are creating new ways to detect these changes in the genome.

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image: Designing In Vitro Models of the Blood-Brain Barrier

Designing In Vitro Models of the Blood-Brain Barrier

By Jyoti Madhusoodanan | September 1, 2016

Choosing the right model, be it 3-D or 2-D, requires wading through varied cell sources, cell types, and cell culture conditions.

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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Pulling It All Together

Pulling It All Together

By Kate Yandell | April 1, 2016

Systems-biology approaches offer new strategies for finding hard-to-identify drug targets for cancer.

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image: Marriages of Opportunity

Marriages of Opportunity

By Jeffrey M. Perkel | February 1, 2016

New ideas for antibody-drug conjugate design

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image: Pluripotency Bots

Pluripotency Bots

By Kate Yandell | January 1, 2016

A tour of efforts to automate the production and differentiation of induced pluripotent stem cells

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