stem cells, techniques

The pandemic spurred innovation in a variety of ways, from CRISPR-based diagnostics to cell biology benchwork at home.

Stem cells from nine snake species respond to tissue culturing techniques previously used only on mouse and human stem cells.

Insulin-producing cells grown in the lab could offer a functional cure for the disease.

The introduced cells engrafted in the nose, became olfactory sensory neurons, and sent axons to the animals’ brains.

Determining which products of advanced biotechnology are deserving of legal protections is essential to our own social architecture.

Cell implants, gene therapy, even optogenetics are making headway in clinical trials to treat various forms of blindness.  

Simultaneous exposure to reprogramming and gene-editing plasmids efficiently produces edited pluripotent colonies.

How to culture stem cells without depending on mouse feeder cells

These engineered “cells” were made from the secretions and membranes of human mesenchymal stem cells.

See researchers' recipe for synthetic mesenchymal stem cells, which showed cardiac regenerative potential in mice.

Researchers identify transcription factors and environmental conditions necessary to reprogram human and mouse cells into cells that function like hematopoietic stem cells.

Sequencing and gene-editing advances make tracing a cell’s journey throughout development easier than ever.

Celebrating 30 years and a resurrection

Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.

Since The Scientist published its first issue in October 1986, life-science research has transformed from a manual and often tedious task to a high-tech, largely automated process of unprecedented efficiency.

Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

Expert tips for isolating and culturing cancer stem cells

Embryonic stem cells likely mucked up the cultures used in the debunked “stimulus-triggered acquisition of pluripotency” studies.

A paper published last month claims that electromagnetic exposure facilitates cell reprogramming, but some scientists question the evidence.