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image: New Methods to Detect CRISPR Off-Target Mutations

New Methods to Detect CRISPR Off-Target Mutations

By Sandeep Ravindran | March 1, 2018

Researchers have developed a variety of techniques to detect when CRISPR misses the mark.

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image: Ready, Set, Grow

Ready, Set, Grow

By Amber Dance | September 1, 2017

How to culture stem cells without depending on mouse feeder cells

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image: The Mechanobiology Garage

The Mechanobiology Garage

By Andy Tay | July 17, 2017

New tools for investigating how physical forces affect cells

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image: A Selection of CRISPR Proof-of-Principle Studies

A Selection of CRISPR Proof-of-Principle Studies

By Kelly Rae Chi | March 1, 2017

Advice on how to deploy the latest techniques in your own lab

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image: Discovering Novel Antibiotics

Discovering Novel Antibiotics

By Sandeep Ravindran | February 1, 2017

Three methods identify and activate silent bacterial gene clusters to uncover new drugs

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image: Characterizing the Imprintome

Characterizing the Imprintome

By Amber Dance | January 1, 2017

Three techniques for identifying the collection of maternal and paternal genes silenced in offspring

3 Comments

image: How to Track Cell Lineages As They Develop

How to Track Cell Lineages As They Develop

By Kelly Rae Chi | December 1, 2016

Sequencing and gene-editing advances make tracing a cells journey throughout development easier than ever.

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image: Techniques for Assessing Genomic Copy Number Variations

Techniques for Assessing Genomic Copy Number Variations

By Sarah C.P. Williams | October 1, 2016

As the importance of genomic copy number variations for health and disease becomes clearer, researchers are creating new ways to detect these changes in the genome.

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image: Designing In Vitro Models of the Blood-Brain Barrier

Designing In Vitro Models of the Blood-Brain Barrier

By Jyoti Madhusoodanan | September 1, 2016

Choosing the right model, be it 3-D or 2-D, requires wading through varied cell sources, cell types, and cell culture conditions.

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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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