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tag history disease medicine human genome project physiology

3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Genetic Variation Illuminates Murky Human History
Douglas Steinberg | Jul 23, 2000 | 8 min read
If humans are 99.9 percent genetically identical, as President Bill Clinton is fond of asserting when he extols the Human Genome Project, that 10th-of-a-percent difference has a lot of explaining to do. How does genetic variation determine a person's unique physical traits? Can it predict someone's susceptibility to a disease? Such questions, pertaining to the present or future, are what occupy most human geneticists. A small group, however, studies genetic variation as a clue to the past. Som
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Svante Pääbo with a skeleton
Svante Pääbo Awarded Nobel for Paleogenomics
Shawna Williams | Oct 3, 2022 | 3 min read
The geneticist’s accomplishments include sequencing Neanderthal DNA and leading the project that identified a new species of hominin, the Denisovans.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Two babies engaged in conversation, with one shouting in the other’s ear
Nurturing Early Language Skills Prevents the Behavioral Expression of a Genetic Trait
Iris Kulbatski, PhD | Jul 11, 2022 | 4 min read
A new precision medicine approach is making life sweeter for infants unable to metabolize milk sugar.
The 0.1% Portrait of Human History
Brendan Maher | Jun 29, 2003 | 7 min read
Stored in the human genome, perhaps, is the record of human evolution and existence on this planet. Many say, however, that this history and the benefits it may unfold for human health cannot be found in the single, essentially complete human sequence--99.9% similar to any other human sequence. It's the 0.1% difference that should tell the tale--not only of migration, war, technological achievement, and conquest--but also of the differences that confer susceptibility to complex, multigenic dis
New Genome Sequences Reveal Undescribed African Migration
Max Kozlov | Oct 29, 2020 | 5 min read
An analysis of the genomes of people from 50 ethnolinguistic groups in Africa spots 62 genes under positive selection and 3 million more genetic variants than previously documented.

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