disease & medicine, cancer

A look at the molecular processes that may feed into the tumor-fighting effects of physical activity

Meet some of the people featured in the April 2020 issue of The Scientist.

Spurred by family tragedy, the medical physicist wants to treat cancer in a new way.

Gene editing can knock out genes crucial to cervical tumor cells’ survival, researchers report.

Strategies to trick, manipulate, and direct the evolution of tumors

Through his studies on cancer-causing viruses, the University of California, Los Angeles, professor has helped develop lifesaving treatments.

By infecting glioblastoma cells but not healthy brain tissue, some form of the virus could serve a therapeutic purpose.

Studies point to a role for physical activity in fighting malignancies, improving treatment outcomes, and fostering overall health in patients.

Ben Franklin was right. An ounce of prevention is worth a pound of cure.

Autonomous, living microrobots that seek and destroy cancer are not as futuristic as one might imagine, thanks to a fusion of robotics and synthetic biology.

New therapeutic approaches in oncology aim to manipulate or block cancer’s adaptation to treatment.

A newly engineered CAR T cell that incorporates a peptide isolated from the venom of the deathstalker scorpion has broad brain tumor–binding capabilities that will be investigated in an upcoming clinical trial.

About one-quarter of the hundreds of genes on the inactivated X chromosome in XX cells manage to escape that silencing, at least some of the time.

When X-linked genes evade silencing on the “inactive” chromosome in XX cells, some protect women from diseases such as cancer, but others seem to promote conditions such as autoimmunity.

A cancer patient who underwent the new fertility preservation procedure successfully gave birth five years after her immature eggs were collected.

In the first clinical study of its kind in the US, researchers used CRISPR to modify CAR T cells to make them more potent against cancer, but the clinical benefits are unknown.

A video chronicles the course of disease research and prompts questions about where scientists may focus their studies in the future.

The Oxford researcher’s work on lipid and peptide antigens revealed key mechanisms in inflammation, immunotherapy, and vaccination, which are being pursued in clinical trial treatments.

Normal hair growth can lead to infection during cancer treatment.