Sam Jaffe | May 18, 2003 | 3 min read
5-Prime | Drug Development: Clinical Trials Who gets tested in Phase I Trials? As many as 80 healthy or sick human beings. Phase I trials occur after animal tissue and whole-animal studies have determined that the agent appears safe and effective for its intended use. This stage discerns mainly whether the agent is safe for humans and provides data to determine the pharmacological effects. Phase I studies, which last from two to six months, are observed closely so that the entire trial can