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image: Custom-Made Molecules

Custom-Made Molecules

By Ruth Williams | August 21, 2017

A new prototype machine can make the biological molecules of one’s choice from digital DNA sequences.

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image: Microbiota Manipulations

Microbiota Manipulations

By Ruth Williams | July 17, 2017

Two research teams develop tools for tinkering with a bacterial genus prominent in human guts.

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These engineered “cells” were made from the secretions and membranes of human mesenchymal stem cells.

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image: Phosphorylation at the Flick of a Switch

Phosphorylation at the Flick of a Switch

By Ruth Williams | May 1, 2017

Incorporating light-controlled dimerization domains into kinases provides tight regulation of these enzymes.

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image: Targeting Tregs Halts Cancer’s Immune Helpers

Targeting Tregs Halts Cancer’s Immune Helpers

By Ruth Williams | April 1, 2017

New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.

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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By Ruth Williams | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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image: Deep Pocket Exploration

Deep Pocket Exploration

By Ruth Williams | February 1, 2017

A modification to traditional docking software enables the examination of a ligand’s passage into its receptor.

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A test tube-based genome-labeling technique has been brought under the microscope.

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image: Synthetic Sensors

Synthetic Sensors

By Ruth Williams | December 1, 2016

Engineered circuits detect endogenous transcription factors to drive cellular outputs.

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image: Neural Connectome Method Uses mRNA Barcodes

Neural Connectome Method Uses mRNA Barcodes

By Ruth Williams | November 1, 2016

Researchers swap microscopy for RNA sequencing to track neural paths in the mouse brain.  

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