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image: Gene Expression Analysis Gets Gassy

Gene Expression Analysis Gets Gassy

By Ruth Williams | June 1, 2018

Soil scientists use a gas-producing reporter system to assess gene activity in bacteria.

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The DIY devices collect data and enable light stimulation, chamber agitation, and gas infusion.

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image: Researchers Make Knockout Stem Cell Lines in One Step

Researchers Make Knockout Stem Cell Lines in One Step

By Ruth Williams | December 1, 2017

Combining gene editing and stem-cell induction improves efficiency of functional genetic analyses.

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image: Implanted Magnetic Probes Measure Brain Activity

Implanted Magnetic Probes Measure Brain Activity

By Ruth Williams | November 1, 2017

Micrometer-size magnetrodes detect activity-generated magnetic fields within living brains.

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image: Live Cell Extractions

Live Cell Extractions

By Ruth Williams | October 1, 2017

Nanostraws that collect specimens from cells without killing them allow for repeated sampling.

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These engineered “cells” were made from the secretions and membranes of human mesenchymal stem cells.

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image: Phosphorylation at the Flick of a Switch

Phosphorylation at the Flick of a Switch

By Ruth Williams | May 1, 2017

Incorporating light-controlled dimerization domains into kinases provides tight regulation of these enzymes.

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image: Targeting Tregs Halts Cancer’s Immune Helpers

Targeting Tregs Halts Cancer’s Immune Helpers

By Ruth Williams | April 1, 2017

New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.

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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By Ruth Williams | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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image: Deep Pocket Exploration

Deep Pocket Exploration

By Ruth Williams | February 1, 2017

A modification to traditional docking software enables the examination of a ligand’s passage into its receptor.

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