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tag virology gene silencing genetics genomics cancer
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
A Master Regulator of Gene Expression
Mariella Bodemeier Loayza Careaga, PhD
| Jan 31, 2024
| 4 min read
A CRISPR-based screening platform helped scientists identify a transcription factor that makes CAR T cells better at killing cancer cells.
Silencing Epigenetic Complexes Re-sensitizes Drug-Resistant Cancer Cells
Rachael Moeller Gorman
| Sep 25, 2023
| 4 min read
Researchers studying lung cancer cell lines found that chromatin remodeling underlies one type of osimertinib resistance.
X Chromosome Silenced in Some Cancers in Males
Natalia Mesa, PhD
| Nov 11, 2022
| 3 min read
A study finds that
XIST
, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males.
Delivering Silence
Sabrina Richards
| Mar 1, 2012
| 2 min read
Using RNA viruses to silence genes could optimize tissue targeting while reducing toxicity.
CRISPR Gene Editing: Cas9 and Beyond
Johanna Pruller, PhD and Deanna MacNeil, PhD
| Nov 29, 2023
| 7 min read
Researchers create and improve CRISPR-Cas mediated gene editing technologies based on prokaryotic CRISPR systems and eukaryotic DNA repair mechanisms.
Jumping Genes’ Role in Cancer
Diana Kwon
| Mar 1, 2023
| 8 min read
Transposons may be key players in how tumors develop and spread, but they also keep cancer at bay in some circumstances.
Translation of “Jumping Genes” Creates Cancer Therapy Targets
Natalia Mesa, PhD
| Mar 29, 2023
| 4 min read
Researchers find many tumor-specific antigens form when cancer genes and transposable elements link up.
Turning on the Bat Signal
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Why Some HPV Infections Carry More Cervical Cancer Risk
Dan Robitzski
| Feb 2, 2023
| 5 min read
Where and how human papillomavirus integrates itself into the human genome steers the infection’s clinical outcomes, finds a large, multifaceted study.
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