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image: Researchers Make Knockout Stem Cell Lines in One Step

Researchers Make Knockout Stem Cell Lines in One Step

By Ruth Williams | December 1, 2017

Combining gene editing and stem-cell induction improves efficiency of functional genetic analyses.

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image: Live Cell Extractions

Live Cell Extractions

By Ruth Williams | October 1, 2017

Nanostraws that collect specimens from cells without killing them allow for repeated sampling.

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image: Microbiota Manipulations

Microbiota Manipulations

By Ruth Williams | July 17, 2017

Two research teams develop tools for tinkering with a bacterial genus prominent in human guts.

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image: Targeting Tregs Halts Cancer’s Immune Helpers

Targeting Tregs Halts Cancer’s Immune Helpers

By Ruth Williams | April 1, 2017

New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.

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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By Ruth Williams | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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A test tube-based genome-labeling technique has been brought under the microscope.

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image: How to Track Translation in Living Cells

How to Track Translation in Living Cells

By Ruth Williams | October 1, 2016

Four independent research groups develop techniques for visualizing peptide production in living cells.

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image: Wanted: Transcriptional Regulators

Wanted: Transcriptional Regulators

By Ruth Williams | August 1, 2016

Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.

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image: A New Way to ID Targets of RNA-Binding Proteins

A New Way to ID Targets of RNA-Binding Proteins

By Ruth Williams | July 1, 2016

The catalytic domain of an RNA-editing enzyme is fused with RNA-binding proteins.

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image: Sensors for All

Sensors for All

By Ruth Williams | May 1, 2016

A versatile modular strategy for detecting small molecules in eukaryotes

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