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cancer, disease & medicine

CRISPR Quashes Cancer in Mice
Rachael Moeller Gorman | Apr 1, 2020 | 3 min read
Gene editing can knock out genes crucial to cervical tumor cells’ survival, researchers report.
Infographic: Researchers Take Aim at Cancer Evolution
Catherine Offord | Apr 1, 2020 | 2 min read
Strategies to trick, manipulate, and direct the evolution of tumors
Cracking Down on Cancer: A Profile of Owen Witte
Diana Kwon | Apr 1, 2020 | 9 min read
Through his studies on cancer-causing viruses, the University of California, Los Angeles, professor has helped develop lifesaving treatments.
Zika as Cancer Buster?
Amy Schleunes | Apr 1, 2020 | 2 min read
By infecting glioblastoma cells but not healthy brain tissue, some form of the virus could serve a therapeutic purpose.
Regular Exercise Helps Patients Combat Cancer
Bente Klarlund Pedersen | Apr 1, 2020 | 10 min read
Studies point to a role for physical activity in fighting malignancies, improving treatment outcomes, and fostering overall health in patients.
Singing the Praises of Prevention
Bob Grant | Apr 1, 2020 | 3 min read
Ben Franklin was right. An ounce of prevention is worth a pound of cure.
Bacteria as Living Microrobots to Fight Cancer
Simone Schuerle and Tal Danino | Apr 1, 2020 | 10+ min read
Autonomous, living microrobots that seek and destroy cancer are not as futuristic as one might imagine, thanks to a fusion of robotics and synthetic biology.
Cancer Researchers Use Evolution to Target Drug Resistance
Catherine Offord | Apr 1, 2020 | 10+ min read
New therapeutic approaches in oncology aim to manipulate or block cancer’s adaptation to treatment.
CAR T Cell Adds Scorpion Venom to Tackle Tumor Heterogeneity
Amy Schleunes | Mar 24, 2020 | 5 min read
A newly engineered CAR T cell that incorporates a peptide isolated from the venom of the deathstalker scorpion has broad brain tumor–binding capabilities that will be investigated in an upcoming clinical trial.
Infographic: How Some X-Chromosome Genes Escape Inactivation
Amber Dance | Mar 1, 2020 | 2 min read
About one-quarter of the hundreds of genes on the inactivated X chromosome in XX cells manage to escape that silencing, at least some of the time.
Genes that Escape Silencing on the Second X Chromosome May Drive Disease
Amber Dance | Mar 1, 2020 | 10+ min read
When X-linked genes evade silencing on the “inactive” chromosome in XX cells, some protect women from diseases such as cancer, but others seem to promote conditions such as autoimmunity.
Baby Born from Egg that Was Matured and Frozen in the Lab
Catherine Offord | Feb 19, 2020 | 2 min read
A cancer patient who underwent the new fertility preservation procedure successfully gave birth five years after her immature eggs were collected.
CRISPR-Edited Cells for Cancer Therapy Safe in Humans: Trial
Ashley Yeager | Feb 6, 2020 | 3 min read
In the first clinical study of its kind in the US, researchers used CRISPR to modify CAR T cells to make them more potent against cancer, but the clinical benefits are unknown.
70 years of disease research graphic
Image of the Day: 70 Years of Disease Research
Amy Schleunes | Jan 21, 2020 | 1 min read
A video chronicles the course of disease research and prompts questions about where scientists may focus their studies in the future.
Immunology Leader Vincenzo Cerundolo Dies
Ashley Yeager | Jan 16, 2020 | 2 min read
The Oxford researcher’s work on lipid and peptide antigens revealed key mechanisms in inflammation, immunotherapy, and vaccination, which are being pursued in clinical trial treatments.
Image of the Day: Inflamed Mouse Follicles
Emily Makowski | Dec 16, 2019 | 2 min read
Normal hair growth can lead to infection during cancer treatment.
Exploring the Matrix: A Profile of Zena Werb
Diana Kwon | Dec 1, 2019 | 7 min read
The cell and molecular biologist unveiled a role for the breakdown of proteins in the extracellular matrix in both healthy and pathogenic cells.
CRISPR-Edited T Cells Used in Cancer Patients for the First Time in the US
Emily Makowski | Nov 6, 2019 | 2 min read
The initial findings from a small clinical trial of patients with multiple myeloma or sarcoma suggest that gene-edited immunotherapy is safe.
Image of the Day: Patient-Derived Organoids
Emily Makowski | Oct 10, 2019 | 1 min read
Three-dimensional tissue cultures grown from cancer patients’ own tumors can predict responses to the drug irinotecan.
Aggressive Cancers Feed Off the Brain’s Nerves
Emily Makowski | Sep 20, 2019 | 2 min read
Three studies show that tumor cells can behave like neurons.
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