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tag disease medicine gene silencing genetics genomics
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
New Strategies to Discover Human Disease Genes
The Scientist
| Oct 16, 2023
| 2 min read
Learn how researchers across health-related fields identify and characterize disease-causing genomic variants.
X Chromosome Silenced in Some Cancers in Males
Natalia Mesa, PhD
| Nov 11, 2022
| 3 min read
A study finds that
XIST
, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males.
Identical Twins Carry Distinctive Epigenetic Marks: Study
Chloe Tenn
| Sep 30, 2021
| 2 min read
Researchers found more than 800 sites in the genome where the twins bore the same chemical tags.
Stem Cell Editing Repairs Severe Immunodeficiency
Kamal Nahas, PhD
| Mar 20, 2024
| 5 min read
Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation.
Translation of “Jumping Genes” Creates Cancer Therapy Targets
Natalia Mesa, PhD
| Mar 29, 2023
| 4 min read
Researchers find many tumor-specific antigens form when cancer genes and transposable elements link up.
Uncovering Rare Disease Genetic Pathways with Global Biobanks
Deanna MacNeil, PhD
| Mar 20, 2023
| 3 min read
Researchers discover new idiopathic pulmonary fibrosis risk factors with multi-ancestry analyses that increase representation of understudied populations.
Silencing Epigenetic Complexes Re-sensitizes Drug-Resistant Cancer Cells
Rachael Moeller Gorman
| Sep 25, 2023
| 4 min read
Researchers studying lung cancer cell lines found that chromatin remodeling underlies one type of osimertinib resistance.
Stepping Into the Unknome
Danielle Gerhard, PhD
| Mar 8, 2024
| 5 min read
A database of neglected genes may help unlock the mysteries hiding in the overlooked regions of the proteome.
Humans Rely on Gut Bacteria for an Enzyme that Prevents Jaundice
Kamal Nahas, PhD
| Feb 16, 2024
| 5 min read
An absence of bilirubin-producing gut microbes may predispose individuals to some diseases, including inflammatory bowel disease.
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