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tag disease medicine virology genetics genomics modus operandi

a person in a white lab coat with a blue glove inserting a clear pcr tube into a which thermocycler while holding an orange box
Coronavirus Mutations Could Muddle COVID-19 PCR Tests
Jack J. Lee | May 17, 2021 | 4 min read
Researchers find that SARS-CoV-2 variants can evade primer-probe sets and recommend that diagnostic assays include multiple targets for reliability.
A fruit bat in the hands of a researcher
How an Early Warning Radar Could Prevent Future Pandemics
Amos Zeeberg, Undark | Feb 27, 2023 | 8 min read
Metagenomic sequencing can help detect unknown pathogens, but its widespread use faces challenges.
Telomeres as the Key to Cancer
Jeffrey Perkel | May 26, 2002 | 9 min read
The standard modus operandi for modeling human diseases in the mouse: Find an interesting gene, knock it out, and watch what happens. In theory, the approach makes perfect sense, and scientists have obtained countless subtle insights into the complexities of biology because of it. But mice, of course, are not humans, and many investigators have had to hastily rewrite otherwise elegant theories because of mouse data. One reason? Researchers have taken for granted that telomere length matters. But
Image shows photorhabdus virulence cassettes (green) binding to insect cells (blue) prior to injection of payload proteins. 
Engineered Bacterial “Syringes” Can Deliver Drugs Into Human Cells
Rohini Subrahmanyam, PhD | Apr 20, 2023 | 4 min read
Researchers repurpose tiny bacterial injection systems to specifically inject a wide variety of proteins into human cells and living mice.
obituary, obituaries, roundup, end of the year, COVID-19, SARS-CoV-2, pandemic, coronavirus, immunology, genetics & genomics, cell & molecular biology, HIV
Those We Lost in 2020
Amanda Heidt | Dec 18, 2020 | 7 min read
The scientific community bid farewell to researchers who furthered the fields of molecular biology, virology, sleep science, and immunology, among others.
The Scientist Staff | Mar 28, 2024
In with the New
Mary Beth Aberlin | Jan 1, 2012 | 3 min read
There is definitely no shortage of technological innovation in the life sciences.
The Bright Side of Prions
Randal Halfmann | Jan 1, 2014 | 10+ min read
Associated with numerous neurological diseases, misfolded proteins may also play decisive roles in normal cellular functioning.
 
Notebook
The Scientist Staff | Mar 2, 1997 | 8 min read
Monday mornings can be tough, even if you're Bill Gates. The head of Redmond, Wash.-based Microsoft Corp. ran into a few glitches at a presentation he was giving at the annual meeting of the American Association for the Advancement of Science (AAAS) in Seattle. In the middle of a demonstration on February 17 aimed at showing how Web browsers and E-mail will soon merge, the modem connection failed. A computer-vision demonstration by a Microsoft researcher didn't work, either. Then, during a ques

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