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tag genetics genomics gene silencing microbiology cancer
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
A Master Regulator of Gene Expression
Mariella Bodemeier Loayza Careaga, PhD
| Jan 31, 2024
| 4 min read
A CRISPR-based screening platform helped scientists identify a transcription factor that makes CAR T cells better at killing cancer cells.
Silencing Epigenetic Complexes Re-sensitizes Drug-Resistant Cancer Cells
Rachael Moeller Gorman
| Sep 25, 2023
| 4 min read
Researchers studying lung cancer cell lines found that chromatin remodeling underlies one type of osimertinib resistance.
X Chromosome Silenced in Some Cancers in Males
Natalia Mesa, PhD
| Nov 11, 2022
| 3 min read
A study finds that
XIST
, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
New Strategies to Discover Human Disease Genes
The Scientist
| Oct 16, 2023
| 2 min read
Learn how researchers across health-related fields identify and characterize disease-causing genomic variants.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD
| Jan 18, 2024
| 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
CRISPR Gene Editing: Cas9 and Beyond
Johanna Pruller, PhD and Deanna MacNeil, PhD
| Nov 29, 2023
| 7 min read
Researchers create and improve CRISPR-Cas mediated gene editing technologies based on prokaryotic CRISPR systems and eukaryotic DNA repair mechanisms.
Jumping Genes’ Role in Cancer
Diana Kwon
| Mar 1, 2023
| 8 min read
Transposons may be key players in how tumors develop and spread, but they also keep cancer at bay in some circumstances.
The Scientist
Staff
| Mar 29, 2024
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