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tag genetics genomics electron microscopy cell molecular biology gene silencing modus operandi

2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
computerized image of different layers of a cell shown at great detail
New Studies Enable a Clearer View Inside Cells
Andrew Chapman | Nov 4, 2021 | 5 min read
Armed with improved imaging techniques and supercomputers, researchers are generating detailed three-dimensional images of cellular structures that anyone can explore.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Top 7 in Molecular Biology
Cristina Luiggi | Aug 16, 2011 | 3 min read
A snapshot of the most highly ranked articles in molecular biology, from Faculty of 1000
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Imaging Chromatin to Deduce Function from Form
Marissa Fessenden | Dec 1, 2018 | 7 min read
Researchers describe their tools for probing how the physical shape of the genome affects genes’ function.
Top 7 in Genomics & Genetics
Bob Grant | Jul 19, 2011 | 3 min read
A snapshot of the most highly ranked articles in genomics, genetics, and related areas, from Faculty of 1000
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
a pair of scissors cuts a film strip that's curled into a helix
Alternative Splicing Provides a Broad Menu of Proteins for Cells
Gabrielle M. Gentile, Hannah J. Wiedner, Emma R. Hinkle, and Jimena Giudice | Jan 13, 2020 | 10+ min read
It’s now clear that gene transcripts can be constructed in various ways, yet many questions remain about the process.
DNA, RNA Probes Help Investigators Narrow The Search For Genes
Holly Ahern | Nov 26, 1995 | 10+ min read
For Genes Author: Holly Ahern For a geneticist, pinpointing a mutation in a human gene that might be responsible for an inherited disease can be likened to the proverbial search for a needle in a haystack. While mo-lecular biologists sift through the 3 billion base pairs in the human genome in search of disease-causing genes, other scientists choose to approach the problem from the perspective of the mouse, a model system for mammal research. Because mice and humans are members of the same gr

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