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salmonella bacteria 3d illustration
Salmonella Injection Helps the Mouse Immune System Kill Tumors
Nanoparticle-coated bacteria can capture tumor antigens and deliver them to immune cells, triggering a response that improved survival rates in mice.
Salmonella Injection Helps the Mouse Immune System Kill Tumors
Salmonella Injection Helps the Mouse Immune System Kill Tumors

Nanoparticle-coated bacteria can capture tumor antigens and deliver them to immune cells, triggering a response that improved survival rates in mice.

Nanoparticle-coated bacteria can capture tumor antigens and deliver them to immune cells, triggering a response that improved survival rates in mice.

bacteria, cancer

Illustration showing how following radiation therapy, which triggers the release of cancer-specific antigens, researchers injected Salmonella typhimurium bacteria covered in positively charged nano- particles near tumors in mice.
Infographic: Salmonella Shuttle Tumor Antigens to Immune Cells
Dan Robitzski | May 16, 2022 | 1 min read
Nanoparticle-coated bacteria carry cancer-derived proteins to dendritic cells, enabling the immune system to launch a response in a mouse model.
Engineered Bacteria Make Tumors More T Cell-Friendly
Engineered Bacteria Make Tumors More T Cell-Friendly
Aparna Nathan, PhD | Apr 8, 2022 | 5 min read
Microbes designed to produce specific immunomodulatory metabolites could give immunotherapy a boost.
Manipulating the Microbiome to Manage Disease
The Scientist Creative Services Team in collaboration with Tecan | 1 min read
Cammie Lesser will discuss how she turns a probiotic into a drug-delivering machine, while Andrew Y. Koh will describe the connection between the gut microbiota and cancer immunotherapy efficacy.
illustration of a blood vessel
Bacteria in Tumors Promote Metastasis in Mice
Sophie Fessl, PhD | Apr 7, 2022 | 3 min read
Microbes living inside cancer cells may help them spread to distant sites by enhancing the cells’ resistance to mechanical stress, a study shows.
A stained tissue sample of metastatic pancreatic cancer
Tetanus Immunity Protects Mice Against Pancreatic Cancer
Amanda Heidt | Mar 24, 2022 | 3 min read
Because most people are vaccinated against tetanus as children, delivering benign bacteria carrying a tetanus antigen into pancreatic tumors makes them visible to memory cells in the immune system, researchers report.
Investigating the Immune Response Using Advanced Flow Cytometry
The Scientist | 1 min read
Discover how researchers are using flow cytometry to delve into the inner workings of the immune life cycle!
Tumor microbiome composite
Could Cancer’s Microbiome Help Diagnose and Treat the Disease?
Jef Akst | Mar 14, 2022 | 10+ min read
A growing appreciation of the bacterial assemblages that live within tumors has researchers striving to understand and capitalize on their role.
Illustration showing microbial signatures of cancer in the body
Infographic: Putting Cancer’s Unique Microbiomes to Use
Jef Akst | Mar 14, 2022 | 1 min read
From diagnosis to tracking treatment responses, bacteria and other microbes in the blood, gut, and tumors of cancer patients may provide helpful hints for improving their care.
Best of Cancer Research
The Scientist | 1 min read
This collection of articles from The Scientist explores some of the latest cancer research!
black-and-white image of an open mouth
The Common Mouth Microbe That Keeps Popping Up in Tumors
David Adam | Dec 15, 2021 | 6 min read
Lab studies link the oral bacteria Fusobacterium nucleatum to cancers from the gut to the head and neck. Could targeting the microbe tackle tumors?
Microbial Signatures in Blood Are Associated with Various Cancers
Shawna Williams | Jul 13, 2020 | 2 min read
A study suggests the potential for a noninvasive diagnostic that could detect tumors early and differentiate between disease types.
Extreme Biotech: Understanding Extremophile Biology to Impact Human Health
The Scientist | 1 min read
Jaclyn Winter and Shiladitya DasSarma will discuss how they harness the unique biology of extremophiles for the discovery and development of new therapeutics.
Infographic: Building Bacteria to Fight Cancer
Simone Schuerle and Tal Danino | Apr 1, 2020 | 3 min read
Researchers are engineering microbes to deliver therapeutics specifically to tumors, maximizing the treatments’ efficacy while minimizing side effects.
Bacteria as Living Microrobots to Fight Cancer
Simone Schuerle and Tal Danino | Apr 1, 2020 | 10+ min read
Autonomous, living microrobots that seek and destroy cancer are not as futuristic as one might imagine, thanks to a fusion of robotics and synthetic biology.
Image of the Day: Inflamed Mouse Follicles
Emily Makowski | Dec 16, 2019 | 2 min read
Normal hair growth can lead to infection during cancer treatment.
Image of the Day: Sentinel Cells
Carolyn Wilke | Jan 16, 2019 | 1 min read
Researchers hacked the genetic machinery of E. coli to make them glow and identify proteins linked to cancer.
Latest Reproducibility Project Study Fails to Replicate
Kerry Grens | Mar 13, 2018 | 2 min read
Researchers did not observe the same link between a bacterium and human colon cancer that prior investigators had reported.
Cancer-Fighting Chemical Found in Human Skin Bacteria
Diana Kwon | Mar 1, 2018 | 2 min read
A molecule produced by a strain of Staphylococcus epidermis interferes with DNA synthesis.
Streptococcus gallolyticus Spurs Colorectal Tumor Growth in Mice
Diana Kwon | Jul 14, 2017 | 2 min read
The bacteria also promoted the growth of human colon cancer cells in a dish.
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