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An APP-knockout neuron (right) shows extended axonal and reduced dendritic growth compared with a normal mouse neuron (left).
Amyloid Precursor Protein Linked to Brain Development Mechanisms
Researchers provide evidence that the Alzheimer’s-associated protein calibrates a signaling pathway that is conserved across the animal kingdom.
Amyloid Precursor Protein Linked to Brain Development Mechanisms
Amyloid Precursor Protein Linked to Brain Development Mechanisms

Researchers provide evidence that the Alzheimer’s-associated protein calibrates a signaling pathway that is conserved across the animal kingdom.

Researchers provide evidence that the Alzheimer’s-associated protein calibrates a signaling pathway that is conserved across the animal kingdom.

membrane proteins, neuroscience

How Vampire Bats Find Veins
Jessica P. Johnson | Aug 4, 2011 | 3 min read
Heat-sensing protein channels in vampire bats allow the flying mammals to find the best place to sink their teeth into their prey.
The Birth of Optogenetics
Edward S. Boyden | Jul 1, 2011 | 10+ min read
An account of the path to realizing tools for controlling brain circuits with light.
OPSINS: Tools of the trade
Edward S. Boyden | Jul 1, 2011 | 1 min read
The optogenetic toolset is composed of genetically encoded molecules that, when targeted to specific neurons in the brain, enable the electrical activity of those neurons to be driven or silenced by light. 
Optogenetics: A Light Switch for Neurons
Edward S. Boyden | Jul 1, 2011 | 1 min read
This animation illustrates optogenetics—a radical new technology for controlling brain activity with light. 
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