Franklin Hoke | Sep 13, 1992 | 8 min read
When the technique of pulsed-field gel electrophoresis (PFGE) was first described by David C. Schwartz and Charles R. Cantor almost a decade ago (Cell, 37:67-75, 1984), many molecular biologists recognized its potential immediately. A flurry of innovation in instrumentation based on the idea followed in the next half-dozen years. Despite this interest and activity, only in the past few years has PFGE secured its place as a mature, integral laboratory tool in molecular genetics generally and the