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A close up of a tick held in a pair of forceps, with Kevin Esvelt’s face out of focus in the background.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
woman in mask on balcony looks at smoky landscape
How Wildfire Smoke Raises Infectious Disease Risk
Amanda Heidt | Sep 8, 2021 | 10+ min read
As fires blanket growing swathes of the West, scientists are beginning to understand more about how their smoke affects the transmission and severity of COVID-19 and other illnesses, and how it differs from that of other types of air pollution.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Migrations influenced immune evolution
Melissa Lee Phillips | Oct 4, 2007 | 3 min read
Human innate immunity differs between Africans and others, perhaps due to different infectious environments
Mapping Disease
Ed Yong | Apr 28, 2013 | 4 min read
Online tools could help to improve our patchy knowledge of the whereabouts of infectious diseases.
a veterinarian in a white hazmat suit holding a small pig
The Long Journey to Resolve the Origins of a Previous Pandemic
Martha Nelson | Sep 2, 2021 | 10+ min read
Dozens of researchers, including myself, worked for years to uncover that swine flu had leapt to humans from a pig in Mexico in 2009. We learned a lot about influenza evolution, pig farming, and outbreak risk along the way.
Plague Genome: The Evolution Of a Pathogen
Ricki Lewis | Oct 28, 2001 | 7 min read
Plague has earned a place in history books as the Black Death of medieval Europe, and in novels, from Albert Camus' classic The Plague, to the more recent Year of Wonders.1,2 A different medium for telling the tale of the plague bacterium Yersinia pestis is its genome, recently sequenced by researchers at the Sanger Centre, the London School of Hygiene and Tropical Medicine, the Royal London School of Medicine and Dentistry, and the Imperial College of Science, Technology and Medicine.3 In addi
A tasmanian devil with its nose in the air
Deadly Facial Tumors Spur Tasmanian Devil Evolution: Study
Christie Wilcox, PhD | Jun 16, 2021 | 6 min read
The largest study to date of the animals’ genetics provides robust evidence that they are adapting to survive a highly lethal, contagious cancer scientists feared would cause their extinction.

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