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tag physiology drug development cell molecular biology literature

A Molecular Switch for Bone Loss
Mariella Bodemeier Loayza Careaga, PhD | Jan 23, 2024 | 4 min read
Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Rethinking Lymphatic Development
Amanda B. Keener | Aug 1, 2015 | 9 min read
Four studies identify alternative origins for cells of the developing lymphatic system, challenging the long-standing view that they all come from veins.
The image shows six different panels containing cells. On each panel, the cells are labelled using a different fluorescent dye that highlights features of a specific organelle within the cells.
Cell Painting: Exploring the Richness of Biological Images
Mariella Bodemeier Loayza Careaga, PhD | Sep 8, 2023 | 4 min read
By coloring different organelles simultaneously, cell painting allows scientists to pick up subtle changes in cell function in response to drugs and other perturbations.
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | Feb 13, 2024 | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Image of an abstract fractal blue and green sea shell.
Cell Chirality Offers Clues to the Mystery of Body Asymmetry
Catherine Offord | Feb 1, 2022 | 10+ min read
Researchers explore the idea that molecular patterns in individual cells could underlie the development of a left and a right in animals.
Lasker Award winner Piet Borst sits at his desk.
A Journey With Metabolism, Parasites, and Cancer
Laura Tran, PhD | Sep 21, 2023 | 7 min read
Piet Borst led stellar work on cell organelles, trypanosomes, and cancer drug resistance during the golden age of biology.

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