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» physiology and genetics & genomics

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The switch from maternal factors involves dynamic reprogramming of the zygotic genome.

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image: Infographic: Understanding Our Diverse Brain

Infographic: Understanding Our Diverse Brain

By Sara B. Linker, Tracy A. Bedrosian, and Fred H. Gage | November 1, 2017

Recent advances in single-cell omics and other techniques are revealing variation at genomic, epigenomic, transcriptomic, and posttranscriptomic levels.

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image: Infographic: Macrophages Around the Body

Infographic: Macrophages Around the Body

By Claire Asher | October 1, 2017

In addition to circulating in the blood as immune sentinels, macrophages play specialized roles in different organs around the body.

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image: Infographic: The Various Forms of Methylated DNA

Infographic: The Various Forms of Methylated DNA

By Skirmantas Kriaucionis | September 1, 2017

To expand the basic nucleotide alphabet, many species modify their DNA with epigenetic marks.

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image: Making the Rounds

Making the Rounds

By Catherine Offord | July 17, 2017

Circular RNA biogenesis occurs when RNA fragments are bent into closed loops of one or more exons and/or introns.

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image: Messing with the Microbiome

Messing with the Microbiome

By Ruth Williams | July 17, 2017

Two new techniques allow researchers to manipulate the activity of gut bacteria. 

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image: Worms’ Epigenetic Memories

Worms’ Epigenetic Memories

By Catherine Offord | July 17, 2017

When kept at warmer temperatures for five generations, C. elegans showed evidence of “remembering” that experience for up to 14 generations.

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image: Infographic: Cook Up an Exome-Based Diet

Infographic: Cook Up an Exome-Based Diet

By Ruth Williams | June 1, 2017

See how scientists designed food with amino acid compositions based on protein-coding regions in the genomes of mice and fruit flies.

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image: Infographic: Plastics’ Effects

Infographic: Plastics’ Effects

By Ee Ling Ng | June 1, 2017

Lab studies suggest that plastic pollutants in the environment could have detrimental effects on animals’ physiology.

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image: Infographic: Single-Cell CRISPR Screens

Infographic: Single-Cell CRISPR Screens

By Ruth Williams | March 1, 2017

See how two new methods track responses to unique genetic manipulations in numerous individual cells in parallel.

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