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tag biochemistry neurodegeneration cancer literature

Fascinated by Folding
Anna Azvolinsky | Aug 3, 2017 | 10 min read
Lila Gierasch uses biochemical tools to understand how linear chains of amino acids turn into complex three-dimensional structures.
Faulty Antibodies Undermine Widespread Research
Ruth Williams | Jan 30, 2020 | 4 min read
Two papers reveal that many commonly used research antibodies don’t bind as believed, highlighting the need to validate these reagents before use.
Mapping Brain Proteins
Devika G. Bansal | Feb 1, 2018 | 7 min read
Researchers are using souped-up mass spectrometry to localize proteins within brain cells.
Neil Bence: Manipulating Degradation
Kerry Grens | Dec 1, 2012 | 3 min read
Senior Scientist, Millennium Pharmaceuticals: The Takeda Oncology Company Age: 39
A Vaulted Mystery
Eufemia S. Putortì and Massimo P. Crippa | Aug 1, 2014 | 10+ min read
Nearly 30 years after the discovery of tiny barrel-shape structures called vaults, their natural functions remain elusive. Nevertheless, researchers are beginning to put these nanoparticles to work in biomedicine.
Prize-Winning PhD
Karen Hopkin | Feb 1, 2010 | 7 min read
By Karen Hopkin Prize-Winning PhD Aaron Ciechanover didn’t set out to win a Nobel Prize for discovering ubiquitin’s all-important role in protein degradation. He was just trying to graduate. © Dan Porges Aaron Ciechanover could not have predicted that the humble system he was studying would play a central role in everything that happens from embryonic development to adulthood. Of course he was just a graduate student at the time. ̶
Mining the Ubiquitin Pathway
John Hall(hall@lifesensors.com) | Dec 4, 2005 | 5 min read
In October 2004, the Royal Swedish Academy of Sciences awarded the Nobel Prize in Chemistry to Aaron Ciechanover, Avram Hersko, and Irwin Rose "for the discovery of ubiquitin-mediated protein degradation."
Top 7 in immunology
Edyta Zielinska | Jan 10, 2011 | 3 min read
A snapshot of the most highly ranked articles in immunology, from Faculty of 1000
Longevity
Jill Adams(juadams@the-scientist.com) | May 8, 2005 | 7 min read
During autophagy-literally "self-eating"-cells deliver cytoplasmic constituents, including whole organelles, to the lysosome for degradation.

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