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image: Exosome Basics

Exosome Basics

By Clotilde Théry | July 1, 2011

Exosomes are small membrane vesicles secreted by most cell types. Internal vesicles form by the inward budding of cellular compartments known as multivesicular endosomes (MVE). 

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image: The Anatomy of a High

The Anatomy of a High

By Thomas Kosten | June 3, 2011

When someone snorts or smokes cocaine, which is composed of small crystalline alkaloid molecules, the drug enters the bloodstream and from there eventually crosses into the heart, brain, and other organs. 

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image: Part Human, Part HIV

Part Human, Part HIV

By Gene M. Shearer and Adriano Boasso | June 3, 2011

Like other enveloped viruses, HIV exits its host cell enshrouded in the cell’s membrane, which contains membrane molecules such as the human leukocyte antigens (HLA). 

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image: Where Cancer and Inflammation Intersect

Where Cancer and Inflammation Intersect

By Giorgio Trinchieri | April 1, 2011

Recent clinical trials have reignited the interest in simple anti-inflammatory drugs like aspirin for controlling the inflammation associated with cancer. 

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image: Epigenetics—A Primer

Epigenetics—A Primer

By Stefan Kubicek | March 1, 2011

Epigenetic events regulate the activities of genes without changing the DNA sequence. Different genes are expressed depending on the methyl-marks attached to DNA itself and by changes in the structure and/or composition of chromatin. 

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image: Stress and Inflammation

Stress and Inflammation

By Christina M. Warboys, Narges Amini, Amalia de Luca, and Paul C. Evans | February 1, 2011

Stress and inflammation Cardiovascular disease, including coronary artery disease and stroke, is the single greatest cause of death worldwide and is a major burden on health services and society. 

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image: Intestinal Molecular Signaling

Intestinal Molecular Signaling

By L. Caetano M. Antunes, Julian E. Davies and B. Brett Finlay | January 1, 2011

Microbes, both good and bad, can exert direct effects on host cells and vice versa. 

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