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tag cancer inflammation neurodegeneration immunology

A Tweak to Immune Cells Reverses Aging in Mice
Abby Olena, PhD | Jan 20, 2021 | 3 min read
Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
Motor neurons, undergoing degeneration in ALS
Mutant T Cells That Drive Amyotrophic Lateral Sclerosis (ALS) Progression May React To a Brain Antigen
Nele Haelterman, PhD | Aug 8, 2022 | 4 min read
Scientists discovered a possibly autoreactive T cell population that forecasts and supports disease progression.
Illustration of bacteriophages infecting a bacterium
Phages Treat Gut Inflammation in Mice
Andy Carstens | Aug 4, 2022 | 5 min read
Mixtures of viruses that attack inflammatory bowel disease–causing bacteria in mice also survive the digestive tract and are well-tolerated in humans, a study finds.
Top 7 in Immunology
Edyta Zielinska | Aug 2, 2011 | 3 min read
A snapshot of the most highly ranked articles in microbiology and related areas, from Faculty of 1000
Macrophages Play a Double Role in Cancer
Amanda B. Keener | Apr 1, 2018 | 10+ min read
Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.
Top 7 in immunology
Edyta Zielinska | Jan 10, 2011 | 3 min read
A snapshot of the most highly ranked articles in immunology, from Faculty of 1000
Immune to Failure
Karen Hopkin | Feb 1, 2013 | 9 min read
With dogged persistence and an unwillingness to entertain defeat, Bruce Beutler discovered a receptor that powers the innate immune response to infections—and earned his share of a Nobel Prize.
Pinpointing the Culprit
Rachel Berkowitz | Jun 1, 2017 | 8 min read
Identifying immune cell subsets with CyTOF

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