Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
Mixtures of viruses that attack inflammatory bowel disease–causing bacteria in mice also survive the digestive tract and are well-tolerated in humans, a study finds.
With dogged persistence and an unwillingness to entertain defeat, Bruce Beutler discovered a receptor that powers the innate immune response to infections—and earned his share of a Nobel Prize.