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image: Not Immune to Fat

Not Immune to Fat

By Kate Yandell | November 1, 2015

The effect of a high-fat diet on murine T cells


image: Antibody-Dependent Enhanced (ADE) Immunity

Antibody-Dependent Enhanced (ADE) Immunity

By Beth Marie Mole | March 2, 2013

The method to the dengue virus's maddening infectiousness.


image: Rhinoviruses Exposed

Rhinoviruses Exposed

By Fred Adler | February 1, 2013

Some of these insidious viruses expertly subvert the host immune system, allowing their unhindered proliferation.


image: Adipose Tissue Metabolism in the Obese

Adipose Tissue Metabolism in the Obese

By Justin Odegaard and Ajay Chawla | December 12, 2012

Fat cells behave differently in obese individuals, causing inflammation and insulin resitance.

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image: Normal Fat Tissue Metabolism

Normal Fat Tissue Metabolism

By Justin Odegaard and Ajay Chawla | December 6, 2012

Adipose tissue plays an immune role in individuals of normal wieght.


image: Ubiquitin Chains in Action

Ubiquitin Chains in Action

By Keith D. Wilkinson and David Fushman | July 1, 2012

Present in every tissue of the body, ubiquitin appears to be involved in a dizzying array of functions, from cell cycle and division to organelle and ribosome biogenesis, as well as the response to viral infection. The protein plays at least two role


image: Telomere Basics

Telomere Basics

By Rodrigo Calado and Neal Young | May 1, 2012

Telomeres are repetitive, noncoding sequences that cap the ends of linear chromosomes. They consist of hexameric nucleotide sequences (TTAGGG in humans) repeated hundreds to thousands of times. 


image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By Vern L. Schramm | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 


image: How Drugs Interact with a Baby’s Parts

How Drugs Interact with a Baby’s Parts

By Edyta Zielinska | March 1, 2012

A lot changes in a child’s body over the course of development, and not all changes occur linearly: gene expression can fluctuate, and organs can perform different functions on the way to their final purpose in the body. Here are some of the key deve


image: Suspected Effects of Vitamin D

Suspected Effects of Vitamin D

By Amy Maxmen | March 1, 2012

Vitamin D has a variety of actions in the body. It binds to the vitamin D receptor (VDR), which then binds to the retinoid X receptor (RXR) and activates the expression of numerous genes. 


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