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» inflammation and neurodegeneration

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image: Infographic: Two Pain Paths Diverge in the Body

Infographic: Two Pain Paths Diverge in the Body

By Mark R. Hutchinson | January 1, 2018

The acute pain that results from injury or disease is very different from chronic pain.

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Emerging evidence links bacterial or viral infection with the neuropathology of Alzheimer’s disease.

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image: Infographic: The Brain on Psychedelics

Infographic: The Brain on Psychedelics

By Diana Kwon | September 1, 2017

Understanding how hallucinogenic drugs affect different neural networks could shed light on their therapeutic potential.

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image: Infographic: Immune Irritation in the Gut

Infographic: Immune Irritation in the Gut

By Catherine Offord | June 1, 2017

A look at how gluten affects patients with celiac disease

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image: A Complex Disorder

A Complex Disorder

By Stephen D. Hursting, Ciara H. O’Flanagan, and Laura W. Bowers | November 1, 2015

Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.  

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image: Not Immune to Fat

Not Immune to Fat

By Kate Yandell | November 1, 2015

The effect of a high-fat diet on murine T cells

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image: Ubiquitin Chains in Action

Ubiquitin Chains in Action

By Keith D. Wilkinson and David Fushman | July 1, 2012

Present in every tissue of the body, ubiquitin appears to be involved in a dizzying array of functions, from cell cycle and division to organelle and ribosome biogenesis, as well as the response to viral infection. The protein plays at least two role

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image: Inflammation, Pain, and Resolvins

Inflammation, Pain, and Resolvins

By Claudia Sommer and Frank Birklein | January 1, 2012

Not all inflammation leads to pain. Despite widespread infection followed by fever, colds rarely cause pain. But when some cytokines and certain immune cells are active near pain-sensing nerves, they trigger receptors that convey pain sensations to the brain.

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image: Lost in Space

Lost in Space

By Carol Barnes | September 1, 2011

Looking for a more realistic way to study memory, we turned to place cells­­—­a network of cells that record a rat’s memory of an environment. 

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image: Molecular Learning

Molecular Learning

By Carol Barnes | September 1, 2011

Long-term potentiation (LTP), discovered in the 1970s, was later shown to be the molecular basis of memory. 

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