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» inflammation and neurodegeneration

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Emerging evidence links bacterial or viral infection with the neuropathology of Alzheimer’s disease.

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image: Infographic: The Brain on Psychedelics

Infographic: The Brain on Psychedelics

By | September 1, 2017

Understanding how hallucinogenic drugs affect different neural networks could shed light on their therapeutic potential.

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image: Infographic: Immune Irritation in the Gut

Infographic: Immune Irritation in the Gut

By | June 1, 2017

A look at how gluten affects patients with celiac disease

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image: A Complex Disorder

A Complex Disorder

By , , and | November 1, 2015

Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.  

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image: Not Immune to Fat

Not Immune to Fat

By | November 1, 2015

The effect of a high-fat diet on murine T cells

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image: Ubiquitin Chains in Action

Ubiquitin Chains in Action

By | July 1, 2012

Present in every tissue of the body, ubiquitin appears to be involved in a dizzying array of functions, from cell cycle and division to organelle and ribosome biogenesis, as well as the response to viral infection. The protein plays at least two role

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image: Inflammation, Pain, and Resolvins

Inflammation, Pain, and Resolvins

By | January 1, 2012

Not all inflammation leads to pain. Despite widespread infection followed by fever, colds rarely cause pain. But when some cytokines and certain immune cells are active near pain-sensing nerves, they trigger receptors that convey pain sensations to the brain.

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image: Lost in Space

Lost in Space

By | September 1, 2011

Looking for a more realistic way to study memory, we turned to place cells­­—­a network of cells that record a rat’s memory of an environment. 

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image: Molecular Learning

Molecular Learning

By | September 1, 2011

Long-term potentiation (LTP), discovered in the 1970s, was later shown to be the molecular basis of memory. 

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image: The Seat of Memory

The Seat of Memory

By | September 1, 2011

Early on, researchers had learned that the hippocampus was the structure in the brain where long-term memories were created and stored, but it was not known whether the different cell types within this structure might be more or less susceptible to the aging process.

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    The Nutshell Research Links Gut Health to Neurodegeneration

    Rodent studies presented at the Society for Neuroscience meeting this week tie pathologies in the gastrointestinal tract or microbiome composition with Parkinson’s and Alzheimer’s diseases.

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