A physician and neurobiologist at the Rockefeller University who specialized in addiction research, Kreek was best known for her work on developing the treatment for heroin addiction.
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Using CRISPR to swap an archaic variant of the NOVA1 gene into human stem cells, researchers create organoids with neurodevelopmental differences from those carrying modern DNA.
Suppressing the natural age-related increase in neuronal excitation lengthens the lives of worms, and there are indications that the same may be true for mice and humans.
Fred H. Gage, Sara B. Linker, and Tracy A. Bedrosian | Nov 1, 2017 | 4 min read
Advances in single-cell technologies have revealed vast differences between cells once thought to be in the same category, calling into question how we define cell type in the first place.
Male scientists stress mice out; using SCNT to reprogram adult cells; acetate can reach mouse brain, reduce appetite; WHO sounds “post-antibiotic era” alarm
Transcriptional landscape of the fetal brain; how a parasitic worm invades plants; difficulties reproducing “breakthrough” heart regeneration method; oxytocin and dishonesty