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» drug development and inflammation

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image: Infographic: A Painful Pathway

Infographic: A Painful Pathway

By Catherine Offord | January 1, 2018

Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.

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image: Infographic: Two Pain Paths Diverge in the Body

Infographic: Two Pain Paths Diverge in the Body

By Mark R. Hutchinson | January 1, 2018

The acute pain that results from injury or disease is very different from chronic pain.

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image: Infographic: Breaking into the Brain

Infographic: Breaking into the Brain

By Amanda B. Keener | November 1, 2017

The blood-brain barrier is a collection of specialized cells and proteins that control the movement of molecules from the blood to the central nervous system.

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Emerging evidence links bacterial or viral infection with the neuropathology of Alzheimer’s disease.

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image: Infographic: The Brain on Psychedelics

Infographic: The Brain on Psychedelics

By Diana Kwon | September 1, 2017

Understanding how hallucinogenic drugs affect different neural networks could shed light on their therapeutic potential.

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image: Infographic: Immune Irritation in the Gut

Infographic: Immune Irritation in the Gut

By Catherine Offord | June 1, 2017

A look at how gluten affects patients with celiac disease

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image: Infographic: Proteasome Basics

Infographic: Proteasome Basics

By John Hines and Craig M. Crews | May 1, 2017

The structure and function of the cell's protein-degrading machine

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image: Infographic: The Cost of Drug Development

Infographic: The Cost of Drug Development

By John D. Loike and Jennifer Miller | February 1, 2017

Expensive clinical trials and few drug approvals can drive up drug prices for consumers.

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image: Infographic: Repurposing Strategies

Infographic: Repurposing Strategies

By Anna Azvolinsky | January 1, 2017

Novel uses for existing and failed drugs may save companies time and money in bringing new therapeutics to market.

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image: A Complex Disorder

A Complex Disorder

By Stephen D. Hursting, Ciara H. O’Flanagan, and Laura W. Bowers | November 1, 2015

Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.  

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