DNA methylation, cell & molecular biology

A clock constructed of rDNA methylation sites can estimate both chronological and biological age across species.

New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.

Methylation on adenine bases is involved in the dampening of gene expression in mammalian cells, according to a study.

After spending more than a decade developing tools to study patterns in gene sequences, bioinformaticians are now working on programs to analyze epigenomics data.

Among the first to discover epigenetic reprogramming during mammalian development, Wolf Reik has been studying the dynamics of the epigenome for 30 years.

The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.

Living conditions in early life can have lasting, widespread effects on DNA methylation.

For the first time researchers have shown that epigenetic changes that increase lifespan can be inherited across multiple generations.

Sheng Wang leaves the Boston University School of Medicine and agrees to retract two published studies.

Testing a central tenet of epigenetic regulation

Did Erasmus Darwin foreshadow the tweaking of his grandson’s paradigm?

Epigenetic events regulate the activities of genes without changing the DNA sequence. Different genes are expressed depending on the methyl-marks attached to DNA itself and by changes in the structure and/or composition of chromatin. 

Research in behavioral epigenetics is seeking evidence that links experience to biochemistry to gene expression and back out again.