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tag hiv evolution vaccine immunology

A germinal center inside a lymph node
Slow Vaccine Delivery May Maximize Immune Response
Alejandra Manjarrez, PhD | Sep 23, 2022 | 5 min read
A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more-effective antibody production against HIV in rhesus monkeys, a study finds.
Roadmap to an HIV Vaccine
Sabrina Richards | Apr 3, 2013 | 3 min read
Researchers track the evolution of HIV in a single patient to understand what drives the production of broadly neutralizing antibodies.
SARS-CoV-2 with Genomic Deletions Escapes an Antibody
Abby Olena, PhD | Feb 16, 2021 | 4 min read
Researchers identify deletions in the N-terminal domain of the spike protein that allow the coronavirus to avoid antibody neutralization and that may contribute to the emergence of new variants.
Illustration showing rod-shaped Mycobacterium tuberculosis bacteria in the lungs of a person with tuberculosis
Delayed T cell Response Allows Tuberculosis to Gain Foothold in Monkeys
Anna Napolitano, PhD | Jun 1, 2022 | 5 min read
The results could help guide the design of new vaccines for the disease.
Defeating the Virus
Wayne C. Koff | May 1, 2015 | 10+ min read
Recent discoveries are spurring a renaissance in HIV vaccine research and development.
Immunity to SARS-CoV-2 Lasts at Least Six Months, Data Show
Ashley Yeager | Nov 23, 2020 | 4 min read
Half a year after infection, people who had recovered from COVID-19 had robust antibodies, along with traces of the virus in their gut, which may drive long-lasting immunity.
Deciphering Immunology's Dirty Secret
Kate Travis | Jan 1, 2007 | 9 min read
Deciphering Immunology's Dirty Secret Can innate immune adjuvants save vaccinology? By Kate Travis ARTICLE EXTRAS 1 Why, he wondered, did scientists have to include bits of bacteria or aluminum hydroxide with a vaccine to get an immune response? Janeway hypothesized and later proved that so-called pattern recognition receptors identify invading pathogens and trigger an immediate reaction against the i
Two-Faced Proteins May Tackle HIV Reservoirs
Amanda B. Keener | Oct 21, 2015 | 3 min read
Researchers design antibody-like proteins to awaken and destroy HIV holdouts.
A Shot in the Arm
Edyta Zielinska | Jun 1, 2011 | 3 min read
Decades of vaccine research have expanded our understanding of the immune system and are yielding novel disease-fighting tactics.
No Mo’ Slow Flow
Jeffrey M. Perkel | Jan 1, 2012 | 7 min read
Tools and tricks for high-throughput flow cytometry

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