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tag ecology whole genome sequencing vivisection clinical trials

2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
A Flood in Genomics
Brendan Maher | Nov 25, 2001 | 9 min read
Nine months have passed since draft sequences of the human genome were first published.1,2 One human gestation period later, the genome, as deciphered by the International Human Genome Sequencing Consortium, still screams toward its projected Spring 2003 finish date. "The trajectory we're on for meeting that goal is precisely on target," assures Francis Collins, director, National Human Genome Research Institute (NHGRI) and spokesperson for the largest public biological science project in histor
Cancer cell
Interrogating the Complexities of the Tumor Microenvironment
Alison Halliday, PhD, Technology Networks | May 19, 2023 | 5 min read
Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.
Speaking of Science
The Scientist | Mar 1, 2011 | 2 min read
Speaking of Science Behavioural Ecology Research Group, Oxford How fleeting are the wishes and efforts of man! how short his time! and consequently how poor will be his results, compared with those accumulated by Nature during whole geological periods! —Charles Darwin, On The Origin of Species (1859)Why them? Why is this species [the New Caledonian crow] on a small island in the Pacific able to not just use but to manufacture a variety of tool
Diagnosing Cancer: A Genomics and Proteomics Approach
Tom Hollon | Sep 21, 2003 | 7 min read
In 1996, Jeff Trent and colleagues published the first paper describing DNA microarrays as tools for pinpointing gene variants underlying various tumor properties.1 Now, as president and scientific director of Translational Genomics Research Institute (TGEN), in Phoenix, Trent is using microarrays to look for gene expression patterns that can be applied to developing diagnostics. The role of microarrays, Trent says, "will be on the discovery side. Testing all 30,000 genes against a diagnosti
Researchers Learn from Plant Viruses to Protect Crops
Claire Asher | Feb 1, 2018 | 10+ min read
Plants are locked in an ancient arms race with hostile viruses, but genome editing is giving crops the upper hand.
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021 | 10+ min read
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
Reducing Malaria to its Constituent Parts
Eugene Russo | May 23, 2004 | 5 min read
FIRST BITE:Courtesy of CDC/Jim GathanyFemale Anopheles gambiae mosquito feeding.A decade ago, scientists around the world recognized that despite malaria's tremendous disease burden, research on the topic had stagnated. With funding at low levels, robust molecular biology tools numbered few. Today, genome sequences for Plasmodium falciparum, the parasite causing malaria, and for Anopheles gambiae, the mosquito that spreads it, have already fundamentally changed the research landscape. Plasmodium
African Sleeping Sickness: A Recurring Epidemic
Ricki Lewis | May 12, 2002 | 5 min read
African trypanosomiasis is making an unwelcome comeback. But unlike other returning diseases, this one has a drug treatment—eflornithine—that disappeared from the market when it failed to cure cancer. Yet like Viagra's origin from a curious side effect in a clinical trial, so too was eflornithine reborn. "When it was discovered that it removes mustaches in women, it suddenly had a market: western women with mustaches," says Morten Rostrup, president of the international council for M

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